Distinct activities of suppressor of cytokine signaling (SOCS) proteins and involvement of the SOCS box in controlling G-CSF signaling (Q40563242)

21 September 2017

title

Distinct activities of suppressor of cytokine signaling (SOCS) proteins and involvement of the SOCS box in controlling G-CSF signaling (English)

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21 September 2017

2

Judith Gits

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21 September 2017

author name string

Gert-Jan M van de Geijn

series ordinal

1

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21 September 2017

Ivo P Touw

series ordinal

3

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21 September 2017

publication date

23 April 2004

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Journal of Leukocyte Biology

21 September 2017

published in

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21 September 2017

volume

76

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21 September 2017

issue

1

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21 September 2017

page(s)

237-244

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Cytokine receptor signalling

21 September 2017

cites work

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IFN regulatory factor-1-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-1 gene promoter by IFN-gamma

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Cloning and characterization of a functional promoter of the human SOCS-3 gene

21 January 2018

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Autoregulation of pituitary corticotroph SOCS-3 expression: characterization of the murine SOCS-3 promoter

21 January 2018

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STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation

21 January 2018

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Twenty proteins containing a C-terminal SOCS box form five structural classes

21 January 2018

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The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.

21 January 2018

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A new protein containing an SH2 domain that inhibits JAK kinases

21 January 2018

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SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation

21 January 2018

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Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction

21 January 2018

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Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells

21 January 2018

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The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

21 January 2018

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Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

21 January 2018

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Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

21 January 2018

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Cloning and characterization of novel CIS family genes

21 January 2018

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Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor

21 January 2018

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Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

21 January 2018

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SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

21 January 2018

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The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

21 January 2018

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The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

21 January 2018

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The N-terminal truncated isoform of SOCS3 translated from an alternative initiation AUG codon under stress conditions is stable due to the lack of a major ubiquitination site, Lys-6.

21 January 2018

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Tyrosine phosphorylation disrupts elongin interaction and accelerates SOCS3 degradation

21 January 2018

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A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box.

21 January 2018

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Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling

21 January 2018

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The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo

21 January 2018

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SOCS3 is a critical physiological negative regulator of G-CSF signaling and emergency granulopoiesis.

21 January 2018

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SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling.

21 January 2018

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Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.

21 January 2018

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Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice

21 January 2018

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Gigantism in mice lacking suppressor of cytokine signalling-2

21 January 2018

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Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation.

21 January 2018

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Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3

21 January 2018

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SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation

21 January 2018

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21 January 2018

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Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

21 January 2018

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A new technique for the assay of infectivity of human adenovirus 5 DNA

21 January 2018

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An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT.

21 January 2018

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A small amphipathic alpha-helical region is required for transcriptional activities and proteasome-dependent turnover of the tyrosine-phosphorylated Stat5

21 January 2018

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Identification of Shp-2 as a Stat5A phosphatase

21 January 2018

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Cytosolic tyrosine dephosphorylation of STAT5. Potential role of SHP-2 in STAT5 regulation

21 January 2018

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Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling

21 January 2018

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Inhibition and restoration of prolactin signal transduction by suppressors of cytokine signaling

21 January 2018

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Large-scale identification of disease genes involved in acute myeloid leukemia

21 January 2018

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Overexpression of SOCS-2 in advanced stages of chronic myeloid leukemia: possible inadequacy of a negative feedback mechanism

21 January 2018

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Role of the Cytokine-inducible SH2 Protein CIS in Desensitization of STAT5b Signaling by Continuous Growth Hormone

21 January 2018

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21 January 2018

Identifiers

DOI

10.1189/JLB.0104041

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21 September 2017

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