HIF-1α and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages (Q40980593)

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scientific article published on 16 April 2015

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English	HIF-1α and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages	scientific article published on 16 April 2015

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scholarly article

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Europe PubMed Central

PMC publication ID

25 September 2017

HIF-1α and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages (English)

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25 September 2017

atherosclerosis

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based on heuristic

inferred from title

José Antonio Enríquez

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25882065%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

María Pimentel-Santillana

4

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9 June 2020

7

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9 June 2020

12

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Ramón Bartrons

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9 June 2020

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Ahmed Tawakol

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9 June 2020

Parmanand Singh

2

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9 June 2020

Marina Mojena

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9 June 2020

Hamed Emami

5

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9 June 2020

Megan MacNabb

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9 June 2020

Jagat Narula

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9 June 2020

Paqui G Través

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9 June 2020

María Fernández-Velasco

11

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9 June 2020

Paloma Martín-Sanz

13

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9 June 2020

Zahi A Fayad

14

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9 June 2020

Alberto Tejedor

15

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9 June 2020

Lisardo Boscá

16

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9 June 2020

language of work or name

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publication date

16 April 2015

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25 September 2017

Arteriosclerosis, Thrombosis, and Vascular Biology

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9 June 2020

35

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9 June 2020

6

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9 June 2020

1463-1471

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9 June 2020

Macrophages in atherosclerosis: a dynamic balance.

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Characterization of resident B cells of vascular walls in human atherosclerotic patients.

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Local proliferation dominates lesional macrophage accumulation in atherosclerosis

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25 September 2017

Role of PFKFB3-driven glycolysis in vessel sprouting

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A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells.

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Nontransformed, GM-CSF-dependent macrophage lines are a unique model to study tissue macrophage functions.

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25 September 2017

Targeting 6-phosphofructo-2-kinase (PFKFB3) as a therapeutic strategy against cancer

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25 September 2017

Hypoxia induces netrin-1 and Unc5b in atherosclerotic plaques: mechanism for macrophage retention and survival

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Hypoxia in murine atherosclerotic plaques and its adverse effects on macrophages

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Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure

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Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart Association

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25 September 2017

Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation

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Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells.

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Block copolymer micelles for controlled delivery of glycolytic enzyme inhibitors

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Hypoxia-inducible factor-2α regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis

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25 September 2017

Macrophages in the pathogenesis of atherosclerosis

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25 September 2017

Hypoxia and inflammation

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Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis

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Macrophage death and defective inflammation resolution in atherosclerosis

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THE METABOLISM OF TUMORS IN THE BODY

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Novel concepts in atherogenesis: angiogenesis and hypoxia in atherosclerosis

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25 September 2017

Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.

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25 September 2017

Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer

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25 September 2017

Why do cancers have high aerobic glycolysis?

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25 September 2017

6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia

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25 September 2017

HIF-1alpha is essential for myeloid cell-mediated inflammation

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Inflammation in atherosclerosis

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Distinct domains of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit mediate activation of Jak/Stat signaling and differentiation

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Measurement of cytokine secretion, intracellular protein expression, and mRNA in resting and stimulated peripheral blood mononuclear cells.

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Macrophage oxygen-dependent antimicrobial activity. III. Enhanced oxidative metabolism as an expression of macrophage activation

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Relevance of the MEK/ERK signaling pathway in the metabolism of activated macrophages: a metabolomic approach.

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17 June 2018

Chronic hypoxia leads to a glycolytic phenotype and suppressed HIF-2 signaling in PC12 cells.

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Hypoxia but not inflammation augments glucose uptake in human macrophages: Implications for imaging atherosclerosis with 18fluorine-labeled 2-deoxy-D-glucose positron emission tomography.

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Relationships Between Oxidative Metabolism, Macrophage Activation, and Antilisterial Activity

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12 December 2020

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10.1161/ATVBAHA.115.305551

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9 June 2020

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9 June 2020

PubMed publication ID

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9 June 2020

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