Topoisomerase IIalpha-dependent induction of a persistent DNA damage response in response to transient etoposide exposure. (Q41130676)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19858003%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Topoisomerase IIalpha-dependent induction of a persistent DNA damage response in response to transient etoposide exposure (English)

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11 February 2020

0 references

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1

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11 February 2020

author name string

Louise Pope

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19858003%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Robert J G Haché

series ordinal

3

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11 February 2020

publication date

9 October 2009

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11 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19858003%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

4

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11 February 2020

page(s)

38-51

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issue

1

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The efficacy of topoisomerase II-targeted anticancer agents reflects the persistence of drug-induced cleavage complexes in cells

11 February 2020

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27 September 2017

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gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

27 September 2017

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A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery

27 September 2017

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Histone H2A phosphorylation in DNA double-strand break repair

27 September 2017

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MDC1 regulates DNA-PK autophosphorylation in response to DNA damage

27 September 2017

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Genetic evidence for involvement of two distinct nonhomologous end-joining pathways in repair of topoisomerase II-mediated DNA damage

27 September 2017

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Sequence-specific potentiation of topoisomerase II inhibitors by the histone deacetylase inhibitor suberoylanilide hydroxamic acid

27 September 2017

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Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA

27 September 2017

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Mechanism and regulation of human non-homologous DNA end-joining

27 September 2017

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Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair

27 September 2017

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Threonines 2638/2647 in DNA-PK are essential for cellular resistance to ionizing radiation

27 September 2017

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The topoisomerase IIbeta circular clamp arrests transcription and signals a 26S proteasome pathway

27 September 2017

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

27 September 2017

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Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks

27 September 2017

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Cellular roles of dna topoisomerases: a molecular perspective

27 September 2017

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Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cells

27 September 2017

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Activation and autoregulation of DNA-PK from structured single-stranded DNA and coding end hairpins

27 September 2017

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Decreased topoisomerase IIalpha expression confers increased resistance to ICRF-193 as well as VP-16 in mouse embryonic stem cells

27 September 2017

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27 September 2017

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27 September 2017

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Etoposide targets topoisomerase IIalpha and IIbeta in leukemic cells: isoform-specific cleavable complexes visualized and quantified in situ by a novel immunofluorescence technique

27 September 2017

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Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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The effect of aphidicolin on DNA synthesis in isolated HeLa cell nuclei

27 September 2017

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DNA topoisomerase II rescue by catalytic inhibitors: a new strategy to improve the antitumor selectivity of etoposide

27 September 2017

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17 June 2018

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Interaction of ionizing radiation with the topoisomerase I poison camptothecin in growing V-79 and HeLa cells.

17 June 2018

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Antagonism between camptothecin and topoisomerase II-directed chemotherapeutic agents in a human leukemia cell line

17 June 2018

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Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells

17 June 2018

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Biochemical kinetics model of DSB repair and induction of gamma-H2AX foci by non-homologous end joining.

17 June 2018

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Cellular processing pathways contribute to the activation of etoposide-induced DNA damage responses.

19 August 2018

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Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.

19 August 2018

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19 August 2018

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19 August 2018

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26 S proteasome-mediated degradation of topoisomerase II cleavable complexes.

19 August 2018

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Effects of the epipodophyllotoxin VP-16-213 on cell cycle traverse, DNA synthesis, and DNA strand size in cultures of human leukemic lymphoblasts.

19 August 2018

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19 August 2018

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Crossref

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2009.09.003

21 January 2018

12 December 2020

A protease pathway for the repair of topoisomerase II-DNA covalent complexes

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Subcellular distribution of the alpha and beta topoisomerase II-DNA complexes stabilized by VM-26

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Identifiers

DOI

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11 February 2020

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24 November 2022

mapped directly with Wikidata item

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11 February 2020

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