Targeting the p53 Pathway in Ewing Sarcoma. (Q41303735)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21197471%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

review article

1 reference

title

Targeting the p53 Pathway in Ewing Sarcoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21197471%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1

1 reference

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19 January 2020

David F. Callen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21197471%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

David M Thomas

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21197471%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Kathleen I Pishas

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21197471%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

publication date

9 December 2010

1 reference

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19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21197471%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

2011

1 reference

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19 January 2020

page(s)

746939

1 reference

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Creative Commons Attribution 3.0 Unported

19 January 2020

copyright license

start time

1 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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April 2022 Public Data File from Crossref

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Loss of tumorigenicity of Ewing's sarcoma cells expressing antisense RNA to EWS-fusion transcripts

1 October 2017

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Induction of the growth inhibitor IGF-binding protein 3 by p53

1 October 2017

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Actinomycin and DNA transcription

1 October 2017

1 reference

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Mechanisms of p53 loss in human sarcomas

1 October 2017

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Cancer. p53, guardian of the genome

1 October 2017

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Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

1 October 2017

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Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis

1 October 2017

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Inactivation of the p53 pathway in retinoblastoma.

17 June 2018

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Frequent alteration of p16(INK4a)/p14(ARF) and p53 pathways in the round cell component of myxoid/round cell liposarcoma: p53 gene alterations and reduced p14(ARF) expression both correlate with poor prognosis.

17 June 2018

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The insulin-like growth factor-I receptor signaling pathways are important for tumorigenesis and inhibition of apoptosis

17 June 2018

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The IGF-I receptor and cancer

17 June 2018

1 reference

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Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Abnormalities of the p53 MDM2 and DCC genes in human leiomyosarcomas

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Frequency and structure of p53 rearrangements in human osteosarcoma

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Frequency and diversity of p53 mutations in childhood rhabdomyosarcoma.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Specific targets in sarcoma and developmental therapeutics.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Mdm2 exerts pro-apoptotic activities by antagonizing insulin-like growth factor-I-mediated survival

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

The Biology of Ewing sarcoma.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

EWS-CREB1: a recurrent variant fusion in clear cell sarcoma--association with gastrointestinal location and absence of melanocytic differentiation.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Expression of the EWS/FLI-1 oncogene in murine primary bone-derived cells Results in EWS/FLI-1-dependent, ewing sarcoma-like tumors

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Significance of HDMX-S (or MDM4) mRNA splice variant overexpression and HDMX gene amplification on primary soft tissue sarcoma prognosis.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: a highly lethal subset associated with poor chemoresponse

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Prognostic relevance of p53 alterations and Mib-1 proliferation index in subgroups of primary liposarcomas

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Prognostic significance of p53 gene mutations and p53 protein expression in synovial sarcomas.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Alterations of the p53, Rb and MDM2 genes in osteosarcoma

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Apoptotic response to oncogenic stimuli: cooperative and antagonistic interactions between c-myb and the growth suppressor p53.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Narrow spectrum of infrequent p53 mutations and absence of MDM2 amplification in Ewing tumours.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

The insulin-like growth factor I receptor: a key to tumor growth?

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

MDM2 and CDK4 gene amplification in Ewing's sarcoma

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

High prevalence ofp53 exon 4 mutations in soft tissue sarcoma

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2011%2F746939

Analysis of the p16INK4 and TP53 tumor suppressor genes in bone sarcoma pediatric patients

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2011%2F746939

p53 abnormalities in different subtypes of human sarcomas

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3005944

Chromosomal Abnormality T(9;22)(Q22;Q12) In an Extraskeletal Myxoid Chondrosarcoma Characterized By Fine Needle Aspiration Cytology, Electron Microscopy, Immunohistochemistry and Dna Flow Cytometry

2 December 2018

1 reference

12 December 2020

Analysis of Ki-ras, p53, and MDM2 genes in uterine leiomyomas and leiomyosarcomas

1 reference

12 December 2020

Fusion of an ETS-family gene, EIAF, to EWS by t(17;22)(q12;q12) chromosome translocation in an undifferentiated sarcoma of infancy

1 reference

12 December 2020

p53 Mutation and MDM2 amplification in human soft tissue sarcomas

1 reference

12 December 2020

p53 and ras mutations in Ewing's sarcoma

1 reference

12 December 2020

Genetic imbalances revealed by comparative genomic hybridization in Ewing tumors

1 reference

12 December 2020

EWSR1-CREB1 and EWSR1-ATF1 Fusion Genes in Angiomatoid Fibrous Histiocytoma

1 reference

12 December 2020

Translocation X;18 in synovial sarcoma

1 reference

12 December 2020

Analysis of the p16INK4, p14ARF, p15, TP53, and MDM2 genes and their prognostic implications in osteosarcoma and Ewing sarcoma

1 reference

12 December 2020

Molecular abnormalities of p53, MDM2, and H-ras in synovial sarcoma

1 reference

12 December 2020

p53 gene mutations in soft-tissue sarcomas--correlations with p53 immunohistochemistry and DNA ploidy

1 reference

12 December 2020

p53 mutations in human tumors with chimericEWS/FLI/1 genes

1 reference

12 December 2020

Clinicopathological significance of cell cycle regulation markers in a large series of genetically confirmed Ewing's Sarcoma Family of Tumors

1 reference

12 December 2020

Prognostic impact of INK4A deletion in Ewing sarcoma

1 reference

12 December 2020

No correlation of c-myc overexpression and p53 mutations in liposarcomas

1 reference

12 December 2020

Mutation analysis of p53 gene in childhood malignant solid tumors

1 reference

12 December 2020

Mutation spectrum of the p53 gene in bone and soft tissue sarcomas

1 reference

12 December 2020

Molecular analysis of the 9p21 locus and p53 genes in Ewing family tumors

1 reference

12 December 2020

Relative quantitation of p53 and MDM2 gene expression in leiomyosarcoma; real-time semi-quantitative reverse transcription-polymerase chain reaction

1 reference

12 December 2020

Fusion of the EWS and WT1 genes in the desmoplastic small round cell tumor

1 reference

12 December 2020

P53 mutations in Ewing's sarcoma

1 reference

12 December 2020

Distinct mdm2/p53 expression patterns in liposarcoma subgroups: implications for different pathogenetic mechanisms

1 reference

12 December 2020

Molecular abnormalities of the p53 pathway in dedifferentiated liposarcoma

1 reference

12 December 2020

Comparison of p53 mutations in patients with localized osteosarcoma and metastatic osteosarcoma

1 reference

12 December 2020

Detection of TP53 gene mutations in human sarcomas

1 reference

12 December 2020

Proceedings: Disease-free survival in children with Ewing's sarcoma treated with radiation therapy and adjuvant four-drug sequential chemotherapy

1 reference

12 December 2020

Prognostic impact of P53 status in Ewing sarcoma

1 reference

12 December 2020

Identifiers

DOI

10.1155/2011/746939

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21197471%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21197471%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

21197471

1 reference