Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis (Q41590197)

4 October 2017

Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis (English)

1 reference

4 October 2017

1 reference

4

1 reference

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12 June 2020

Natasha Barteneva

6

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12 June 2020

Christopher R Chin

7

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12 June 2020

author name string

Gaurav D Gaiha

1

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12 June 2020

Kevin J McKim

2

1 reference

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12 June 2020

Matthew Woods

3

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12 June 2020

Janine Rohrbach

5

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12 June 2020

Dongfang Liu

8

1 reference

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12 June 2020

Damien Z Soghoian

9

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12 June 2020

Kevin Cesa

10

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12 June 2020

Shannon Wilton

11

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12 June 2020

Michael T Waring

12

1 reference

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12 June 2020

Adam Chicoine

13

1 reference

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12 June 2020

Travis Doering

14

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12 June 2020

E John Wherry

15

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12 June 2020

Daniel E Kaufmann

16

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12 June 2020

Mathias Lichterfeld

17

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12 June 2020

Abraham L Brass

18

1 reference

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12 June 2020

Bruce D Walker

19

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12 June 2020

language of work or name

English

0 references

publication date

8 December 2014

1 reference

4 October 2017

1 reference

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12 June 2020

volume

41

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12 June 2020

issue

6

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12 June 2020

page(s)

1001-1012

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The c-FLIPL cleavage product p43FLIP promotes activation of extracellular signal-regulated kinase (ERK), nuclear factor κB (NF-κB), and caspase-8 and T cell survival

12 June 2020

cites work

1 reference

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Simultaneous TCR and CD244 signals induce dynamic downmodulation of CD244 on human antiviral T cells.

6 June 2018

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Unravelling the mechanisms of durable control of HIV-1.

6 June 2018

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TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species

6 June 2018

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HIV-specific CD8+ T cells from elite controllers are primed for survival.

6 June 2018

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Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell-mediated deletion.

6 June 2018

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High-dimensional immunomonitoring models of HIV-1-specific CD8 T-cell responses accurately identify subjects achieving spontaneous viral control

6 June 2018

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Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory.

6 June 2018

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Visualization and quantitation of the expression of microRNAs and their target genes in neuroblastoma single cells using imaging cytometry.

6 June 2018

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Programmed necrosis: backup to and competitor with apoptosis in the immune system

6 June 2018

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A human memory T cell subset with stem cell-like properties

6 June 2018

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Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

6 June 2018

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RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation

6 June 2018

1 reference

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6 June 2018

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Low doses of the novel caspase-inhibitor GS-9450 leads to lower caspase-3 and -8 expression on peripheral CD4+ and CD8+ T-cells

6 June 2018

1 reference

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TRIM5 is an innate immune sensor for the retrovirus capsid lattice

6 June 2018

1 reference

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Mechanisms of necroptosis in T cells

6 June 2018

1 reference

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Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection

6 June 2018

1 reference

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

6 June 2018

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Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology

6 June 2018

1 reference

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Caspase-3 is transiently activated without cell death during early antigen driven expansion of CD8(+) T cells in vivo

6 June 2018

1 reference

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Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF

6 June 2018

1 reference

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Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis

6 June 2018

1 reference

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Enzymatically active single chain caspase-8 maintains T-cell survival during clonal expansion

6 June 2018

1 reference

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Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features.

6 June 2018

1 reference

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Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

6 June 2018

1 reference

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Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells

6 June 2018

1 reference

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Death receptor signal transducers: nodes of coordination in immune signaling networks

6 June 2018

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Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control

6 June 2018

1 reference

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Impaired Hepatitis C Virus (HCV)-Specific Effector CD8+ T Cells Undergo Massive Apoptosis in the Peripheral Blood during Acute HCV Infection and in the Liver during the Chronic Phase of Infection

6 June 2018

1 reference

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Spatial differences in active caspase-8 defines its role in T-cell activation versus cell death

6 June 2018

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Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

6 June 2018

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Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.

6 June 2018

1 reference

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A human phenome-interactome network of protein complexes implicated in genetic disorders

6 June 2018

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Death effector domain DEDa, a self-cleaved product of caspase-8/Mch5, translocates to the nucleus by binding to ERK1/2 and upregulates procaspase-8 expression via a p53-dependent mechanism

6 June 2018

1 reference

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Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection

6 June 2018

1 reference

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

6 June 2018

1 reference

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Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

6 June 2018

1 reference

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Antigen recognition induces phosphatidylserine exposure on the cell surface of human CD8+ T cells

6 June 2018

1 reference

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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

6 June 2018

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

6 June 2018

1 reference

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Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells

6 June 2018

1 reference

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Activation of caspases-8 and -10 by FLIP(L).

6 June 2018

1 reference

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Activation-induced cell death in T cells

6 June 2018

1 reference

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Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

6 June 2018

1 reference

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Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

6 June 2018

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

6 June 2018

1 reference

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Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses.

6 June 2018

1 reference

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Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells

6 June 2018

1 reference

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6 June 2018

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Altered expression of tyrosine kinases of the Src and Syk families in human T-cell leukemia virus type 1-infected T-cell lines

6 June 2018

1 reference

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Transfer of CD8+ T cell memory using Bcl-2 as a marker

6 June 2018

1 reference

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RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome

19 August 2018

1 reference

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Dysregulation of TNFα-induced necroptotic signaling in chronic lymphocytic leukemia: suppression of CYLD gene by LEF1.

19 August 2018

1 reference

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HIV-specific CD8+ T-cell proliferation is prospectively associated with delayed disease progression.

19 August 2018

1 reference

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NecroX as a novel class of mitochondrial reactive oxygen species and ONOO⁻ scavenger.

19 August 2018

1 reference

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Reduced cytotoxic function of effector CD8+ T cells is responsible for indoleamine 2,3-dioxygenase-dependent immune suppression.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312487

Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

19 August 2018

1 reference

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HIV-specific CD8+ T cells exhibit markedly reduced levels of Bcl-2 and Bcl-xL.

19 August 2018

1 reference

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Increased CD95/Fas-induced apoptosis of HIV-specific CD8(+) T cells.

19 August 2018

1 reference

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Downregulation of Bcl-2, but not of Bax or Bcl-x, is associated with T lymphocyte apoptosis in HIV infection and restored by antiretroviral therapy or by interleukin 2

19 August 2018

1 reference

12 December 2020

HIV-1 specific CD8+ T cells with an effector phenotype and control of viral replication

1 reference

12 December 2020

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

1 reference

12 December 2020

Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

1 reference

12 December 2020

10.1016/J.IMMUNI.2014.12.011

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25526311%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25526311%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

PubMed publication ID

25526311

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25526311%20AND%20SRC:MED&resulttype=core&format=json