Programmed necrosis: backup to and competitor with apoptosis in the immune system (Q37956879)

25 August 2017

Programmed necrosis: backup to and competitor with apoptosis in the immune system (English)

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25 August 2017

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Jiahuai Han

1

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25 August 2017

Chuan-Qi Zhong

series ordinal

2

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25 August 2017

Duan-Wu Zhang

series ordinal

3

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25 August 2017

language of work or name

English

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publication date

16 November 2011

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25 August 2017

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25 August 2017

12

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25 August 2017

1143-1149

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25 August 2017

12

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RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein

25 August 2017

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12 December 2020

Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis

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12 December 2020

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

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12 December 2020

Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis.

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12 December 2020

Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8

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12 December 2020

Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA.

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12 December 2020

NF-kappaB protects macrophages from lipopolysaccharide-induced cell death: the role of caspase 8 and receptor-interacting protein

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12 December 2020

Involvement of heat shock protein-70 in the mechanism of hydrogen peroxide-induced DNA damage: the role of lysosomes and iron

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12 December 2020

Functional complementation between FADD and RIP1 in embryos and lymphocytes

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12 December 2020

Proteolytic mechanisms in necrotic cell death and neurodegeneration

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12 December 2020

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

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12 December 2020

Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis

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12 December 2020

Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.

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12 December 2020

Induction of necrosis in human neutrophils by Shigella flexneri requires type III secretion, IpaB and IpaC invasins, and actin polymerization

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12 December 2020

Molecular mechanisms of necroptosis: an ordered cellular explosion

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12 December 2020

The requirements for Fas-associated death domain signaling in mature T cell activation and survival

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12 December 2020

Fas and Fas ligand: lpr and gld mutations

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12 December 2020

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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12 December 2020

Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.

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12 December 2020

Physiological cell death of chondrocytes in vivo is not confined to apoptosis. New observations on the mammalian growth plate

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12 December 2020

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

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12 December 2020

Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation

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12 December 2020

Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors

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12 December 2020

Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death

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12 December 2020

The role of PARP activation in glutamate-induced necroptosis in HT-22 cells

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12 December 2020

Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses

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12 December 2020

Rapid, noninflammatory and PS-dependent phagocytic clearance of necrotic cells

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12 December 2020

Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain.

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12 December 2020

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

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12 December 2020

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

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12 December 2020

Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway

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12 December 2020

Mechanisms of necroptosis in T cells

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12 December 2020

The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

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12 December 2020

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

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12 December 2020

Toll-like receptor 3 signaling attenuates liver regeneration

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12 December 2020

Virulent Shigella flexneri causes damage to mitochondria and triggers necrosis in infected human monocyte-derived macrophages

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12 December 2020

The mode of death of pig kidney cells infected with cowpox virus is governed by the expression of the crmA gene

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12 December 2020

RIPK1 is not essential for TNFR1-induced activation of NF-kappaB.

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12 December 2020

Apoptosis in the development and maintenance of the immune system

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12 December 2020

Receptor-interacting protein (RIP) kinase family.

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12 December 2020

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

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12 December 2020

Regulation and function of IKK and IKK-related kinases

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12 December 2020

TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death

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12 December 2020

Receptor interacting protein 3 suppresses vascular smooth muscle cell growth by inhibition of the phosphoinositide 3-kinase-Akt axis

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12 December 2020

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

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12 December 2020

Viral strategies for the evasion of immunogenic cell death

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12 December 2020

NALP inflammasomes: a central role in innate immunity.

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12 December 2020

Tumour-necrosis-factor-mediated cytotoxicity is correlated with phospholipase-A2 activity, but not with arachidonic acid release per se.

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12 December 2020

Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease

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12 December 2020

Association of lysosomal activity with sensitivity and resistance to tumor necrosis factor in murine L929 cells.

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12 December 2020

Death by a thousand cuts: granzyme pathways of programmed cell death

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12 December 2020

Manipulation of host cell death pathways during microbial infections

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12 December 2020

The role of the kinases RIP1 and RIP3 in TNF-induced necrosis

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12 December 2020

Caspase-8 deficiency in T cells leads to a lethal lymphoinfiltrative immune disorder

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12 December 2020

Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury.

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12 December 2020

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

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12 December 2020

How apoptosis got the immune system in shape

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12 December 2020

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

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12 December 2020

Resistance to tumor necrosis factor-induced cell death mediated by PMCA4 deficiency

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12 December 2020

Nitration of the mitochondrial complex I subunit NDUFB8 elicits RIP1- and RIP3-mediated necrosis

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12 December 2020

Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.

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12 December 2020

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

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12 December 2020

Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity

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12 December 2020

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

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12 December 2020

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

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12 December 2020

Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization

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12 December 2020

Ceramide induces non-apoptotic cell death in human glioma cells

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12 December 2020

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

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12 December 2020

Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation

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12 December 2020

Metaxin deficiency alters mitochondrial membrane permeability and leads to resistance to TNF-induced cell killing

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12 December 2020

Role of caspase-8 in hepatocyte response to infection and injury in mice

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12 December 2020

The fate of epithelial cells in the human large intestine

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12 December 2020

Phagocytosis of necrotic cells by macrophages is phosphatidylserine dependent and does not induce inflammatory cytokine production

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12 December 2020

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

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12 December 2020

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

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12 December 2020

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

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12 December 2020

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

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12 December 2020

Intertwined pathways of programmed cell death in immunity

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12 December 2020

Necroptosis as an alternative form of programmed cell death

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12 December 2020

Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles

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12 December 2020

TNF-alpha induces two distinct caspase-8 activation pathways

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12 December 2020

FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells

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12 December 2020

Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.

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12 December 2020

Macrophages in the pathogenesis of atherosclerosis

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12 December 2020

Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor alpha-induced cell death

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12 December 2020

DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB

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12 December 2020

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

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12 December 2020

Caspase-8 serves both apoptotic and nonapoptotic roles

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12 December 2020

Virus inhibition of RIP3-dependent necrosis

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12 December 2020

Lysosomal membrane permeabilization in cell death

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12 December 2020

The role of lysosomal rupture in neuronal death

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12 December 2020

Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis

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12 December 2020

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

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12 December 2020

Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation

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12 December 2020

Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release

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12 December 2020

The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells

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12 December 2020

Cutting edge: innate immunity conferred by B cells is regulated by caspase-8.

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12 December 2020

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

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12 December 2020

Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury.

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Crossref

https://api.crossref.org/works/10.1038%2FNI.2159

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NI.2159

1 reference

25 August 2017

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