Death receptor signal transducers: nodes of coordination in immune signaling networks (Q37417486)

20 August 2017

1 reference

title

Death receptor signal transducers: nodes of coordination in immune signaling networks (English)

1 reference

20 August 2017

Nicholas S Wilson

1

1 reference

20 August 2017

Vishva Dixit

series ordinal

2

1 reference

20 August 2017

Avi Ashkenazi

series ordinal

3

1 reference

20 August 2017

language of work or name

English

0 references

publication date

19 March 2009

1 reference

20 August 2017

1 reference

20 August 2017

10

1 reference

20 August 2017

348-355

1 reference

20 August 2017

4

1 reference

The CD95 Receptor: Apoptosis Revisited

20 August 2017

1 reference

12 December 2020

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis

1 reference

12 December 2020

The generation of protective memory-like CD8+ T cells during homeostatic proliferation requires CD4+ T cells

1 reference

12 December 2020

Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling

1 reference

12 December 2020

TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis

1 reference

12 December 2020

Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival

1 reference

12 December 2020

A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2.

1 reference

12 December 2020

Molecular cloning and characterization of mouse caspase-8

1 reference

12 December 2020

CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.

1 reference

12 December 2020

Developmental pathways that generate natural-killer-cell diversity in mice and humans

1 reference

12 December 2020

Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine, TRAIL.

1 reference

12 December 2020

1 reference

12 December 2020

1 reference

12 December 2020

B-cell receptor and Fas-mediated signals for life and death

1 reference

12 December 2020

Normal thymocyte negative selection in TRAIL-deficient mice

1 reference

12 December 2020

CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation

1 reference

12 December 2020

Cellular FLICE-inhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex

1 reference

12 December 2020

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

1 reference

12 December 2020

Critical link between TRAIL and CCL20 for the activation of TH2 cells and the expression of allergic airway disease

1 reference

12 December 2020

The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation.

1 reference

12 December 2020

CD95 stimulation results in the formation of a novel death effector domain protein-containing complex

1 reference

12 December 2020

The CD95(APO-1/Fas) DISC and beyond

1 reference

12 December 2020

Activation of caspases-8 and -10 by FLIP(L).

1 reference

12 December 2020

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

1 reference

12 December 2020

A New TRADDition in intracellular antiviral signaling

1 reference

12 December 2020

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

1 reference

12 December 2020

Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses

1 reference

12 December 2020

NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy

1 reference

12 December 2020

Evolutionary struggles between NK cells and viruses

1 reference

12 December 2020

Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection.

1 reference

12 December 2020

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

1 reference

12 December 2020

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

1 reference

12 December 2020

The E3 ubiquitin ligase Itch in T cell activation, differentiation, and tolerance

1 reference

12 December 2020

In vivo natural killer cell activities revealed by natural killer cell-deficient mice

1 reference

12 December 2020

The suicide in the thymus, a twisted trail

1 reference

12 December 2020

TNF regulates thymocyte production by apoptosis and proliferation of the triple negative (CD3-CD4-CD8-) subset

1 reference

12 December 2020

Involvement of cellular death in TRAIL/DR5-dependent suppression induced by CD4(+)CD25(+) regulatory T cells

1 reference

12 December 2020

Mathematical modeling identified c-FLIP as an apoptotic switch in death receptor induced apoptosis.

1 reference

12 December 2020

Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor.

1 reference

12 December 2020

A Function of Fas-Associated Death Domain Protein in Cell Cycle Progression Localized to a Single Amino Acid at Its C-Terminal Region

1 reference

12 December 2020

Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer

1 reference

12 December 2020

The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors

1 reference

12 December 2020

Identification and functional characterization of DR6, a novel death domain-containing TNF receptor

1 reference

12 December 2020

Natural killer cell developmental pathways: a question of balance.

1 reference

12 December 2020

MAP kinase kinase kinases and innate immunity

1 reference

12 December 2020

NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation

1 reference

12 December 2020

Antigen-mediated T cell expansion regulated by parallel pathways of death

1 reference

12 December 2020

p53-dependent impairment of T-cell proliferation in FADD dominant-negative transgenic mice

1 reference

12 December 2020

Apoptosis by death factor

1 reference

12 December 2020

Monocyte and macrophage heterogeneity

1 reference

12 December 2020

Targeting the extrinsic apoptosis pathway in cancer

1 reference

12 December 2020

Fas ligand costimulates the in vivo proliferation of CD8+ T cells

1 reference

12 December 2020

Roles of caspase-8 and caspase-10 in innate immune responses to double-stranded RNA

1 reference

12 December 2020

Human dendritic cells mediate cellular apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

1 reference

12 December 2020

Mutational analyses of c-FLIPR, the only murine short FLIP isoform, reveal requirements for DISC recruitment

1 reference

12 December 2020

Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation

1 reference

12 December 2020

TRAIL-R as a negative regulator of innate immune cell responses.

1 reference

12 December 2020

The TNF and TNF receptor superfamilies: integrating mammalian biology

1 reference

12 December 2020

Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation

1 reference

12 December 2020

Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1

1 reference

12 December 2020

Multistep pathogenesis of autoimmune disease.

1 reference

12 December 2020

Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

1 reference

12 December 2020

Life and death in peripheral T cells

1 reference

12 December 2020

c-FLIP protects mature T lymphocytes from TCR-mediated killing

1 reference

12 December 2020

Tumor necrosis factor: an apoptosis JuNKie?

1 reference

12 December 2020

TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis

1 reference

12 December 2020

Cutting Edge: CpG DNA inhibits dendritic cell apoptosis by up-regulating cellular inhibitor of apoptosis proteins through the phosphatidylinositide-3'-OH kinase pathway.

1 reference

12 December 2020

N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway

1 reference

12 December 2020

Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling

1 reference

12 December 2020

Conditional Fas-associated death domain protein (FADD): GFP knockout mice reveal FADD is dispensable in thymic development but essential in peripheral T cell homeostasis

1 reference

12 December 2020

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

1 reference

12 December 2020

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

1 reference

12 December 2020

Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

1 reference

12 December 2020

The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

1 reference

12 December 2020

Role of tumor necrosis factor-related apoptosis-inducing ligand in immune response to influenza virus infection in mice

1 reference

12 December 2020

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

1 reference

12 December 2020

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

1 reference

12 December 2020

Autoimmune lymphoproliferative syndrome

1 reference

12 December 2020

The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes

1 reference

12 December 2020

Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

1 reference

12 December 2020

The regulation of CD95 (Fas) ligand expression in primary T cells: induction of promoter activation in CD95LP-Luc transgenic mice

1 reference

12 December 2020

Targeting death and decoy receptors of the tumour-necrosis factor superfamily

1 reference

12 December 2020

TRAIL deficiency does not rescue impaired CD8+ T cell memory generated in the absence of CD4+ T cell help

1 reference

12 December 2020

TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway

1 reference

12 December 2020

Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation.

1 reference

12 December 2020

A new class of reverse signaling costimulators belongs to the TNF family

1 reference

12 December 2020

c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation

1 reference

12 December 2020

Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL-/- mice

1 reference

12 December 2020

Selective modulation of protein kinase C-theta during T-cell activation

1 reference

12 December 2020

Fas and Fas ligand in gut and liver

1 reference

12 December 2020

Spatial differences in active caspase-8 defines its role in T-cell activation versus cell death

1 reference

12 December 2020

Regulation of TNFR1 and CD95 signalling by receptor compartmentalization

1 reference

12 December 2020

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

1 reference

12 December 2020

Up-regulation of c-FLIP short by NFAT contributes to apoptosis resistance of short-term activated T cells

1 reference

12 December 2020

RIP1, a kinase on the crossroads of a cell's decision to live or die

1 reference

12 December 2020

Rapid up-regulation of c-FLIP expression by BCR signaling through the PI3K/Akt pathway inhibits simultaneously induced Fas-mediated apoptosis in murine B lymphocytes

1 reference

12 December 2020

Fas-mediated cytotoxicity by freshly isolated natural killer cells

1 reference

12 December 2020

Distinct signaling pathways in TRAIL- versus tumor necrosis factor-induced apoptosis

1 reference

12 December 2020

Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation

1 reference

12 December 2020

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

1 reference

12 December 2020

Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity.

1 reference

12 December 2020

Cellular FLICE-inhibitory protein is required for T cell survival and cycling

1 reference

12 December 2020

Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells

1 reference

12 December 2020

Requirement for caspase-8 in NF-kappaB activation by antigen receptor.

1 reference

12 December 2020

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

1 reference

12 December 2020

Steady-state and inflammatory dendritic-cell development

1 reference

12 December 2020

Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity

1 reference

12 December 2020

Priming of T cells to Fas-mediated proliferative signals by interleukin-7

1 reference

12 December 2020

TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver

1 reference

12 December 2020

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

1 reference

12 December 2020

FLICE-inhibitory protein expression during macrophage differentiation confers resistance to fas-mediated apoptosis

1 reference

12 December 2020

TNF-alpha induces two distinct caspase-8 activation pathways

1 reference

12 December 2020

The TRAIL apoptotic pathway in cancer onset, progression and therapy

1 reference

12 December 2020

Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

1 reference

12 December 2020

Antiviral response by natural killer cells through TRAIL gene induction by IFN-alpha/beta

1 reference

12 December 2020

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

1 reference

12 December 2020

Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL.

1 reference

12 December 2020

Cell cycle effects by C-FADD depend on its C-terminal phosphorylation site.

1 reference

12 December 2020

Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity

1 reference

12 December 2020

Tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis is an important endogenous mechanism for resistance to liver metastases in murine renal cancer

1 reference

12 December 2020

TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

1 reference

12 December 2020

The long isoform of cellular FLIP is essential for T lymphocyte proliferation through an NF-kappaB-independent pathway

1 reference

12 December 2020

Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors.

1 reference

12 December 2020

New insights into NF-kappaB regulation and function.

1 reference

12 December 2020

Phosphorylation and ubiquitination of the IkappaB kinase complex by two distinct signaling pathways

1 reference

12 December 2020

High endothelial venules of the lymph nodes express Fas ligand.

1 reference

12 December 2020

IL-15 as a mediator of CD4+ help for CD8+ T cell longevity and avoidance of TRAIL-mediated apoptosis

1 reference

12 December 2020

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

1 reference

12 December 2020

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

1 reference

12 December 2020

Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand

1 reference

12 December 2020

The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation

1 reference

12 December 2020

Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death.

1 reference

12 December 2020

Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation

1 reference

12 December 2020

(Un)expected roles of c-IAPs in apoptotic and NFkappaB signaling pathways

1 reference

12 December 2020

Selective knockdown of the long variant of cellular FLICE inhibitory protein augments death receptor-mediated caspase-8 activation and apoptosis.

1 reference

12 December 2020

The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells

1 reference

12 December 2020

Shared principles in NF-kappaB signaling

1 reference

12 December 2020

Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8.

1 reference

12 December 2020

Death receptors: signaling and modulation

1 reference

12 December 2020

cFLIP regulation of lymphocyte activation and development

1 reference

12 December 2020

Genetic disorders of programmed cell death in the immune system

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.1714

1 reference

20 August 2017

1 reference