Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance (Q41715654)

7 October 2017

Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance (English)

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7 October 2017

12

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4 June 2020

Andrew K Sewell

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4 June 2020

Ondrej Stepanek

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4 June 2020

author name string

Arvind S Prabhakar

2

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4 June 2020

Celine Osswald

3

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4 June 2020

Carolyn G King

4

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4 June 2020

Anna Bulek

5

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4 June 2020

Dieter Naeher

6

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4 June 2020

Marina Beaufils-Hugot

7

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4 June 2020

Michael L Abanto

8

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4 June 2020

Virginie Galati

9

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4 June 2020

Barbara Hausmann

10

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4 June 2020

Rosemarie Lang

11

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4 June 2020

Eric S Huseby

13

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4 June 2020

Arup K Chakraborty

15

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4 June 2020

Ed Palmer

16

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4 June 2020

language of work or name

English

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publication date

2 October 2014

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7 October 2017

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4 June 2020

volume

159

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4 June 2020

issue

2

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4 June 2020

page(s)

333-345

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describes a project that uses

4 June 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4304671/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Lck availability during thymic selection determines the recognition specificity of the T cell repertoire

6 June 2018

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6 June 2018

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The Serial Engagement Model 17 Years After: From TCR Triggering to Immunotherapy

6 June 2018

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Kinetics and mechanics of two-dimensional interactions between T cell receptors and different activating ligands

6 June 2018

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Structural and biophysical determinants of αβ T-cell antigen recognition

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Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation

6 June 2018

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6 June 2018

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Two-stage cooperative T cell receptor-peptide major histocompatibility complex-CD8 trimolecular interactions amplify antigen discrimination

6 June 2018

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Mechanisms for T cell receptor triggering

6 June 2018

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CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery

6 June 2018

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Constitutively active Lck kinase in T cells drives antigen receptor signal transduction

6 June 2018

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Fast on-rates allow short dwell time ligands to activate T cells

6 June 2018

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The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness.

6 June 2018

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TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity.

6 June 2018

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6 June 2018

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T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity

6 June 2018

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Origin of the sharp boundary that discriminates positive and negative selection of thymocytes

6 June 2018

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Low ligand requirement for deletion and lack of synapses in positive selection enforce the gauntlet of thymic T cell maturation

6 June 2018

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6 June 2018

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6 June 2018

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Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model

6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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Self-reactivity in thymic double-positive cells commits cells to a CD8 alpha alpha lineage with characteristics of innate immune cells.

18 August 2018

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The CD3 chains of the T cell antigen receptor associate with the ZAP-70 tyrosine kinase and are tyrosine phosphorylated after receptor stimulation

18 August 2018

1 reference

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How the T Cell Repertoire Becomes Peptide and MHC Specific

18 August 2018

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Affinity threshold for thymic selection through a T-cell receptor-co-receptor zipper

2 December 2018

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12 December 2020

High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling

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12 December 2020

Cutting edge: negative selection of immature thymocytes by a few peptide-MHC complexes: differential sensitivity of immature and mature T cells

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12 December 2020

CD8+ T cell activation is governed by TCR-peptide/MHC affinity, not dissociation rate

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12 December 2020

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Identifiers

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release_iifxww42fzg5rpxodq6u5fhxxe

4 June 2020

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mapped directly with Wikidata item

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4 June 2020

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