Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen. (Q41789528)

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2 February 2020

title

Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen (English)

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2 February 2020

2

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2 February 2020

Judith M E M Cosemans

3

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2 February 2020

Jeffery D. Molkentin

9

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2 February 2020

Alastair W Poole

11

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4

Olga Konopatskaya

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2 February 2020

1

Karen Gilio

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2 February 2020

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Michael Leitges

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2 February 2020

author name string

Imke C A Munnix

5

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2 February 2020

Lenneke Prinzen

6

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2 February 2020

Qinghang Liu

8

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2 February 2020

Johan W M Heemskerk

10

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2 February 2020

language of work or name

English

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publication date

17 May 2010

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Journal of Biological Chemistry

2 February 2020

published in

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volume

285

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issue

30

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2 February 2020

page(s)

23410-23419

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Protein kinase Calpha: disease regulator and therapeutic target.

2 February 2020

cites work

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PKCtheta in platelet activation.

6 June 2018

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PKCtheta is required for hemostasis and positive regulation of thrombin-induced platelet aggregation and alpha-granule secretion

6 June 2018

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6 June 2018

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6 June 2018

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PKCalpha regulates platelet granule secretion and thrombus formation in mice

6 June 2018

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6 June 2018

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Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation

6 June 2018

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Segregation of platelet aggregatory and procoagulant microdomains in thrombus formation: regulation by transient integrin activation

6 June 2018

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PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation

6 June 2018

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P2Y1 and P2Y12 receptors for ADP desensitize by distinct kinase-dependent mechanisms.

6 June 2018

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Regulation of outside-in signaling in platelets by integrin-associated protein kinase C beta

6 June 2018

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Platelet-collagen responses: molecular basis and therapeutic promise

6 June 2018

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PKC-alpha regulates cardiac contractility and propensity toward heart failure

6 June 2018

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6 June 2018

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Direct Demonstration of Involvement of Protein Kinase Cα in the Ca2+-induced Platelet Aggregation

6 June 2018

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Physical and functional interaction between protein kinase C delta and Fyn tyrosine kinase in human platelets

6 June 2018

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Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation

6 June 2018

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Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta

6 June 2018

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Interaction of Bruton's tyrosine kinase and protein kinase Ctheta in platelets. Cross-talk between tyrosine and serine/threonine kinases

6 June 2018

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Ragged spiking of free calcium in ADP-stimulated human platelets: regulation of puff-like calcium signals in vitro and ex vivo

6 June 2018

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Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen

6 June 2018

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Effects of knockout of the protein kinase C beta gene on glucose transport and glucose homeostasis

6 June 2018

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Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow.

6 June 2018

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Synergy between Ca2+ and protein kinase C is the major factor in determining the level of secretion from human platelets

6 June 2018

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The relationship between cytosolic Ca2+, sn-1,2-diacylglycerol and inositol 1,4,5-trisphosphate elevation in platelet-activating-factor-stimulated rabbit platelets. Influence of protein kinase C on production of signal molecules

6 June 2018

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The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

6 June 2018

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6 June 2018

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6 June 2018

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6 June 2018

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18 August 2018

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18 August 2018

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18 August 2018

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Principal role of glycoprotein VI in alpha2beta1 and alphaIIbbeta3 activation during collagen-induced thrombus formation

18 August 2018

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Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood

18 August 2018

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18 August 2018

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18 August 2018

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Identification of protein kinase Calpha as an essential, but not sufficient, cytosolic factor for Ca2+-induced alpha- and dense-core granule secretion in platelets

18 August 2018

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18 August 2018

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A New Protein Kinase C, nPKCη′, and nPCKθ Are Expressed in Human Platelets: Involvement of nPKCη′ and nPKCθ in Signal Transduction Stimulated by PAF

18 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M110.136176

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M110.136176

Translocation of protein kinase C isozymes in thrombin-stimulated human platelets. Correlation with 1,2-diacylglycerol levels

21 January 2018

1 reference

12 December 2020

Selective regulation of protein kinase C isoenzymes by oleic acid in human platelets

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12 December 2020

Ca2+ efflux from platelets. Control by protein kinase C and the filling state of the intracellular Ca2+ stores

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12 December 2020

Collagen but not fibrinogen surfaces induce bleb formation, exposure of phosphatidylserine, and procoagulant activity of adherent platelets: evidence for regulation by protein tyrosine kinase-dependent Ca2+ responses

1 reference

12 December 2020

Differential involvement of tyrosine and serine/threonine kinases in platelet integrin alphaIIbbeta3 exposure

1 reference

12 December 2020

Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRgamma deficiency

1 reference

12 December 2020

PAR-1-dependent pp60src activation is dependent on protein kinase C and increased [Ca2+]: evidence that pp60src does not regulate PAR-1-dependent Ca2+ entry in human platelets

1 reference

12 December 2020

Discovery of potent and selective PKC-theta inhibitors

1 reference

12 December 2020

Dual role of platelet protein kinase C in thrombus formation: stimulation of pro-aggregatory and suppression of procoagulant activity in platelets

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12 December 2020

Induction of the fibrinogen receptor on human platelets by intracellular mediators

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12 December 2020

Different translocation of three distinct PKC isoforms with tumor-promoting phorbol ester in human platelets

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.136176

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20479008%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20479008%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

20479008

1 reference