Human papillomavirus type 16 E7 oncoprotein inhibits the anaphase promoting complex/cyclosome activity by dysregulating EMI1 expression in mitosis (Q41863345)

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scientific article published on 5 September 2013

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English	Human papillomavirus type 16 E7 oncoprotein inhibits the anaphase promoting complex/cyclosome activity by dysregulating EMI1 expression in mitosis	scientific article published on 5 September 2013

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scholarly article

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Europe PubMed Central

13 October 2017

Human papillomavirus type 16 E7 oncoprotein inhibits the anaphase promoting complex/cyclosome activity by dysregulating EMI1 expression in mitosis (English)

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Europe PubMed Central

13 October 2017

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Europe PubMed Central

13 October 2017

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Yueyang Yu

1

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Europe PubMed Central

13 October 2017

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5 September 2013

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Europe PubMed Central

13 October 2017

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Europe PubMed Central

13 October 2017

446

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13 October 2017

1-2

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Europe PubMed Central

13 October 2017

251-259

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13 October 2017

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3799973/fullTextXML

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Control the host cell cycle: viral regulation of the anaphase-promoting complex

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Emi1 preferentially inhibits ubiquitin chain elongation by the anaphase-promoting complex

1 reference

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Human papillomavirus type 16 E7 oncoprotein engages but does not abrogate the mitotic spindle assembly checkpoint

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Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor

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Overexpression of the anaphase promoting complex/cyclosome inhibitor Emi1 leads to tetraploidy and genomic instability of p53-deficient cells

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Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1

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Identifiers

10.1016/J.VIROL.2013.08.013

1 reference

Europe PubMed Central

13 October 2017

1 reference

Europe PubMed Central

13 October 2017

1 reference

Europe PubMed Central

13 October 2017

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