Lysosome-dependent degradation of Notch3. (Q41901351)

13 October 2017

Lysosome-dependent degradation of Notch3. (English)

1 reference

13 October 2017

Lijun Jia

1

1 reference

13 October 2017

Genggeng Yu

series ordinal

2

1 reference

13 October 2017

Yanmei Zhang

series ordinal

3

1 reference

13 October 2017

Michael M Wang

series ordinal

4

1 reference

13 October 2017

6 September 2009

1 reference

International Journal of Biochemistry & Cell Biology

13 October 2017

1 reference

13 October 2017

41

1 reference

13 October 2017

12

1 reference

13 October 2017

2594-2598

1 reference

Thrombospondin 2 potentiates notch3/jagged1 signaling

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

AIP4/Itch regulates Notch receptor degradation in the absence of ligand

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

NOTCH3 signaling pathway plays crucial roles in the proliferation of ErbB2-negative human breast cancer cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Conserved signal peptide of Notch3 inhibits interaction with proteasome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Notch3 gene amplification in ovarian cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Notch signaling in vascular development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

c-Cbl binding and ubiquitin-dependent lysosomal degradation of membrane-associated Notch1.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Ligand endocytosis drives receptor dissociation and activation in the Notch pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: members of the Notch signalling pathway in Drosophila.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Notch signaling: cell fate control and signal integration in development

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

The Notch1 receptor is cleaved constitutively by a furin-like convertase

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Drosophila HOPS and AP-3 complex genes are required for a Deltex-regulated activation of notch in the endosomal trafficking pathway

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Notch1 and Notch2 receptors influence progressive hair graying in a dose-dependent manner.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Notch3 signaling initiates choroid plexus tumor formation.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

Snail is required for Delta endocytosis and Notch-dependent activation of single-minded expression.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2811749

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19735738

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chromosome 19 translocation, overexpression of Notch3, and human lung cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19735738

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BIOCEL.2009.08.019

1 reference

13 October 2017

1 reference

13 October 2017

1 reference