Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I (Q42021514)

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Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I (English)

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Joshua A. Beckman

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Francesco Paneni

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Mark A Creager

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1 August 2013

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European Heart Journal

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Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation

5 June 2018

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Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice

5 June 2018

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Endothelial function: cardiac events

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Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

5 June 2018

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Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease

5 June 2018

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Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I.

5 June 2018

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Report of the expert committee on the diagnosis and classification of diabetes mellitus

5 June 2018

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Diabetes and atherosclerosis: epidemiology, pathophysiology, and management

5 June 2018

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Insulin signalling and the regulation of glucose and lipid metabolism

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Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

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Platelet dysfunction in type 2 diabetes

5 June 2018

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Mechanisms underlying endothelial dysfunction in diabetes mellitus

5 June 2018

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Cellular mechanisms of insulin resistance

5 June 2018

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Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

5 June 2018

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The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years

5 June 2018

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Contributions of polyol pathway to oxidative stress in diabetic cataract.

5 June 2018

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Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction

5 June 2018

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Effects of diabetes and level of glycemia on all-cause and cardiovascular mortality. The San Antonio Heart Study

5 June 2018

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The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

5 June 2018

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Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease

5 June 2018

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Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes.

5 June 2018

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Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells

17 August 2018

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Rosiglitazone improves endothelial function in patients with type 2 diabetes treated with insulin.

17 August 2018

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Glucose oscillations, more than constant high glucose, induce p53 activation and a metabolic memory in human endothelial cells.

17 August 2018

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Circulating CD31+/Annexin V+ microparticles correlate with cardiovascular outcomes

17 August 2018

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Hypothesis: the "metabolic memory", the new challenge of diabetes

17 August 2018

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Simultaneous control of hyperglycemia and oxidative stress normalizes enhanced thrombin generation in type 1 diabetes.

17 August 2018

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Dysglycaemia, cardiovascular outcome and treatment. Is the jury still out?

17 August 2018

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Usefulness of atherogenic dyslipidemia for predicting cardiovascular risk in patients with angiographically defined coronary artery disease.

17 August 2018

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Insulin resistance as a determinant of platelet activation in obese women.

17 August 2018

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Effects of hyperglycemia and hyperinsulinemia on circulating tissue factor procoagulant activity and platelet CD40 ligand.

17 August 2018

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Platelet inhibition by insulin is absent in type 2 diabetes mellitus.

17 August 2018

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Metformin improves endothelial function in patients with metabolic syndrome.

17 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Diabetes induces p66shc gene expression in human peripheral blood mononuclear cells: relationship to oxidative stress.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Selective inhibition of protein kinase Cbeta2 prevents acute effects of high glucose on vascular cell adhesion molecule-1 expression in human endothelial cells

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Anti-inflammatory and profibrinolytic effect of insulin in acute ST-segment-elevation myocardial infarction

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: the role of protein kinase C and NAD(P)H-oxidase activation

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

High glucose causes upregulation of cyclooxygenase-2 and alters prostanoid profile in human endothelial cells: role of protein kinase C and reactive oxygen species

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Increased activity of endogenous endothelin in patients with type II diabetes mellitus

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3743069

Relation of improvement in endothelium-dependent flow-mediated vasodilation after rosiglitazone to changes in asymmetric dimethylarginine, endothelin-1, and C-reactive protein in nondiabetic patients with the metabolic syndrome

17 August 2018

1 reference

12 December 2020

Downregulation of microRNA-126 in endothelial progenitor cells from diabetes patients, impairs their functional properties, via target gene Spred-1

1 reference

12 December 2020

Involvement of microparticles in diabetic vascular complications

1 reference

12 December 2020

The recovery of platelet cyclooxygenase activity explains interindividual variability in responsiveness to low-dose aspirin in patients with and without diabetes

1 reference

12 December 2020

Blockade of the nuclear factor-κB pathway in the endothelium prevents insulin resistance and prolongs life spans

1 reference

12 December 2020

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells

1 reference

12 December 2020

Endothelial nuclear factor κB in obesity and aging: is endothelial nuclear factor κB a master regulator of inflammation and insulin resistance?

1 reference

12 December 2020

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

1 reference

12 December 2020

High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells

1 reference

12 December 2020

Identifiers

DOI

10.1093/EURHEARTJ/EHT149

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23641007%20AND%20SRC:MED&resulttype=core&format=json