Human immune system development and survival of non-obese diabetic (NOD)-scid IL2rγ(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells (Q42254467)

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scientific article published on December 2013

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English	Human immune system development and survival of non-obese diabetic (NOD)-scid IL2rγ(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells	scientific article published on December 2013

Statements

scholarly article

1 reference

Europe PubMed Central

19 October 2017

Human immune system development and survival of non-obese diabetic (NOD)-scid IL2rγ(null) (NSG) mice engrafted with human thymus and autologous haematopoietic stem cells (English)

1 reference

Europe PubMed Central

19 October 2017

0 references

author name string

L Covassin

1

1 reference

Europe PubMed Central

19 October 2017

S Jangalwe

2

1 reference

Europe PubMed Central

19 October 2017

N Jouvet

3

1 reference

Europe PubMed Central

19 October 2017

J Laning

4

1 reference

Europe PubMed Central

19 October 2017

L Burzenski

5

1 reference

Europe PubMed Central

19 October 2017

L D Shultz

6

1 reference

Europe PubMed Central

19 October 2017

M A Brehm

7

1 reference

Europe PubMed Central

19 October 2017

publication date

1 December 2013

1 reference

Europe PubMed Central

19 October 2017

Clinical and Experimental Immunology

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Europe PubMed Central

19 October 2017

174

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Europe PubMed Central

19 October 2017

372-388

1 reference

Europe PubMed Central

19 October 2017

3

1 reference

Europe PubMed Central

19 October 2017

Humanized mice for the study of type 1 and type 2 diabetes

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Humanized mice as a preclinical tool for infectious disease and biomedical research

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Improving human hemato-lymphoid-system mice by cytokine knock-in gene replacement

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Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

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The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function

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Humanized mice in translational biomedical research

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New insights into the regulation of T cells by gamma(c) family cytokines

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Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice

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NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

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Experimental models to study development and function of the human immune system in vivo

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Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

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Development of a human adaptive immune system in cord blood cell-transplanted mice.

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A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-/- gammac-/- double-mutant mice

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Humanized mouse models to study human diseases

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Superior human leukocyte reconstitution and susceptibility to vaginal HIV transmission in humanized NOD-scid IL-2Rγ(-/-) (NSG) BLT mice.

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A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.

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Systemic human T cell developmental processes in humanized mice cotransplanted with human fetal thymus/liver tissue and hematopoietic stem cells.

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Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.

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Development of functional human immune system with the transplantations of human fetal liver/thymus tissues and expanded hematopoietic stem cells in RAG2-/-gamma(c)-/- MICE.

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A model for personalized in vivo analysis of human immune responsiveness

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Analysis of the CD1 antigen presenting system in humanized SCID mice

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Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans.

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Homeostatic expansion and phenotypic conversion of human T cells depend on peripheral interactions with APCs

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Human natural regulatory T cell development, suppressive function, and postthymic maturation in a humanized mouse model

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Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model

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Macrophages prevent human red blood cell reconstitution in immunodeficient mice

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Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice

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Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.

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Full reconstitution of human platelets in humanized mice after macrophage depletion

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Humoral immune responses in humanized BLT mice immunized with West Nile virus and HIV-1 envelope proteins are largely mediated via human CD5+ B cells

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Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice

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Alpha interferon and HIV infection cause activation of human T cells in NSG-BLT mice

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Pig islet xenograft rejection in a mouse model with an established human immune system.

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Rapid evolution of HIV-1 to functional CD8⁺ T cell responses in humanized BLT mice

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HIV-infected T cells are migratory vehicles for viral dissemination

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An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model

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Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice

1 reference

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21 January 2018

Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice

1 reference

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Generation of HIV latency in humanized BLT mice

1 reference

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One percent tenofovir applied topically to humanized BLT mice and used according to the CAPRISA 004 experimental design demonstrates partial protection from vaginal HIV infection, validating the BLT model for evaluation of new microbicide candidates

1 reference

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21 January 2018

HIV latency in the humanized BLT mouse

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HIV infection affects parietal-dependent spatial cognition: evidence from mental rotation and hierarchical pattern perception.

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21 January 2018

RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice

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Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras

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Human breast milk and antiretrovirals dramatically reduce oral HIV-1 transmission in BLT humanized mice

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Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4+CD8+ thymocytes.

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Graft versus host disease in the bone marrow, liver and thymus humanized mouse model

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Major histocompatibility complex (MHC) class I KbDb -/- deficient mice possess functional CD8+ T cells and natural killer cells

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NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection

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Humanized mice for immune system investigation: progress, promise and challenges

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Comparison of human cord blood engraftment between immunocompromised mouse strains

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Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus

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11-color, 13-parameter flow cytometry: identification of human naive T cells by phenotype, function, and T-cell receptor diversity

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IL-2 receptor γ-chain molecule is critical for intestinal T-cell reconstitution in humanized mice

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Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.

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Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.

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Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function

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Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2rγ null mice is enhanced by transgenic expression of membrane-bound human SCF.

1 reference

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New perspectives on the biology of acute GVHD.

1 reference

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T-cell tolerance: central and peripheral

1 reference

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Organization of thymic medullary epithelial heterogeneity: implications for mechanisms of epithelial differentiation.

1 reference

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Role of the gut microbiota in immunity and inflammatory disease

1 reference

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Functional and phenotypic characterization of the humanized BLT mouse model

2 references

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https://pubmed.ncbi.nlm.nih.gov/23869841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient peripheral construction of functional human regulatory CD4(+)CD25(high)Foxp3(+) T cells in NOD/SCID mice grafted with fetal human thymus/liver tissues and CD34(+) cells

1 reference

https://api.crossref.org/works/10.1111%2FCEI.12180

21 January 2018

Transfer of a functional human immune system to mice with severe combined immunodeficiency

1 reference

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21 January 2018

Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23869841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/23869841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intra-bone marrow transplantation of human CD34(+) cells into NOD/LtSz-scid IL-2rgamma(null) mice permits multilineage engraftment without previous irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23869841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23869841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irradiation injury to the developing nervous system: mechanisms of neuronal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/23869841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stem cell factor and hematopoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23869841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human peripheral blood CD4 T cell-engrafted non-obese diabetic-scid IL2rγ(null) H2-Ab1 (tm1Gru) Tg (human leucocyte antigen D-related 4) mice: a mouse model of human allogeneic graft-versus-host disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23869841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/CEI.12180

1 reference

Europe PubMed Central

19 October 2017

0 references

1 reference

Europe PubMed Central

19 October 2017

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