Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state (Q42260307)

19 October 2017

Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state (English)

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19 October 2017

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19 October 2017

Sebastian Königsberger

object named as

Sebastian Königsberger

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author name string

Jan Prodöhl

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19 October 2017

Vanessa Weis

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19 October 2017

Martin Andreas

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19 October 2017

Martin Stehling

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19 October 2017

Theresa Schumacher

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19 October 2017

Ruben Böhmer

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19 October 2017

Ina Thielmann

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19 October 2017

Judith M M van Eeuwijk

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19 October 2017

Bernhard Nieswandt

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19 October 2017

language of work or name

English

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publication date

22 June 2012

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19 October 2017

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19 October 2017

3363-3374

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describes a project that uses

19 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3411075/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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26 October 2017

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26 October 2017

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A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity

26 October 2017

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26 October 2017

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In vivo BLyS/BAFF neutralization ameliorates islet-directed autoimmunity in nonobese diabetic mice

26 October 2017

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26 October 2017

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Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions.

26 October 2017

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Distinct roles for Syk and ZAP-70 during early thymocyte development

26 October 2017

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Structural basis for the inhibition of tyrosine kinase activity of ZAP-70

26 October 2017

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The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade

26 October 2017

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Fcgamma receptors: old friends and new family members

26 October 2017

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Predominant autoantibody production by early human B cell precursors

26 October 2017

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Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity

26 October 2017

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Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop

26 October 2017

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Autoreactive B cells in the marginal zone that express dual receptors

26 October 2017

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Genetics of type 1A diabetes

26 October 2017

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The SH2 domain containing tyrosine phosphatase-1 down-regulates activation of Lyn and Lyn-induced tyrosine phosphorylation of the CD19 receptor in B cells

26 October 2017

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The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils

26 October 2017

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The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling

26 October 2017

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Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases

26 October 2017

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26 October 2017

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Syk tyrosine kinase required for mouse viability and B-cell development

26 October 2017

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Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

26 October 2017

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Molecular aspects of B-lymphocyte activation

26 October 2017

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26 October 2017

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The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chain

26 October 2017

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26 October 2017

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Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

26 October 2017

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The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein

26 October 2017

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Migrant mu+ delta+ and static mu+ delta- B lymphocyte subsets.

26 October 2017

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Antigen receptor tail clue.

29 May 2018

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Deal watch: high hopes for oral SYK inhibitor in rheumatoid arthritis.

16 June 2018

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Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis.

17 August 2018

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Redundant role for Zap70 in B cell development and activation

17 August 2018

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Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion.

17 August 2018

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Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells

17 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411075

Bruton's tyrosine kinase and SLP-65 regulate pre-B cell differentiation and the induction of Ig light chain gene rearrangement.

17 August 2018

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Requirements for follicular exclusion and competitive elimination of autoantigen-binding B cells.

17 August 2018

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Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion.

17 August 2018

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Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia

17 August 2018

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Flow cytometric detection of activated mouse integrin alphaIIbbeta3 with a novel monoclonal antibody

17 August 2018

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Impaired precursor B cell differentiation in Bruton's tyrosine kinase-deficient mice.

17 August 2018

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Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling

17 August 2018

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Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.169

Genetics of Type 1A Diabetes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.169

CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis

21 January 2018

1 reference

12 December 2020

Analysis of Lyn/CD22 double-deficient B cells in vivo demonstrates Lyn- and CD22-independent pathways affecting BCR regulation and B cell survival

1 reference

12 December 2020

T cell activation by clustered tyrosine kinases

1 reference

12 December 2020

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice

1 reference

12 December 2020

Regulation of Autoimmune Diabetes by Complete Freund's Adjuvant Is Mediated by NK Cells

1 reference

12 December 2020

Inflammation and bone erosion are suppressed in models of rheumatoid arthritis following treatment with a novel Syk inhibitor

1 reference

12 December 2020

Censoring of autoreactive B cell development by the pre-B cell receptor

1 reference

12 December 2020

The SHP-1 protein tyrosine phosphatase negatively modulates glucose homeostasis

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2012.169

1 reference

19 October 2017

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19 October 2017

PubMed publication ID

22728826

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