Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection. (Q42282987)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23866914%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection (English)

1 reference

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5 March 2020

8

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5 March 2020

Marylyn Addo

9

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5 March 2020

Alicja Piechocka-Trocha

7

object named as

Alicja Piechocka-Trocha

1 reference

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5 March 2020

author name string

Stephanie Jost

1

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5 March 2020

Uriel Y Moreno-Nieves

2

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5 March 2020

Wilfredo F Garcia-Beltran

3

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5 March 2020

Keith Rands

4

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5 March 2020

Jeff Reardon

5

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5 March 2020

Ildiko Toth

6

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5 March 2020

publication date

18 July 2013

1 reference

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5 March 2020

1 reference

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5 March 2020

volume

10

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5 March 2020

page(s)

74

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https://scigraph.springernature.com/pub.10.1186/1742-4690-10-74

5 March 2020

exact match

0 references

cites work

TIM-3 does not act as a receptor for galectin-9.

1 reference

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Galectin-9 functionally impairs natural killer cells in humans and mice

26 October 2017

1 reference

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Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

26 October 2017

1 reference

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Tim-3 negatively regulates cytotoxicity in exhausted CD8+ T cells in HIV infection

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750478

Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection

26 October 2017

1 reference

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Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicity

26 October 2017

1 reference

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Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9

26 October 2017

1 reference

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Natural killer cells act as rheostats modulating antiviral T cells

26 October 2017

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HIV-1 adaptation to NK-cell-mediated immune pressure

26 October 2017

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Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry

26 October 2017

1 reference

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Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy

26 October 2017

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Reduced frequencies of NKp30+NKp46+, CD161+, and NKG2D+ NK cells in acute HCV infection may predict viral clearance.

26 October 2017

1 reference

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TIM-3 and its regulatory role in immune responses

26 October 2017

1 reference

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Innate immunity defines the capacity of antiviral T cells to limit persistent infection

26 October 2017

1 reference

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T cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3) mediates natural killer cell suppression in chronic hepatitis B.

26 October 2017

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T Cell/Transmembrane, Ig, and Mucin-3 Allelic Variants Differentially Recognize Phosphatidylserine and Mediate Phagocytosis of Apoptotic Cells

26 October 2017

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HIV protective KIR3DL1 and HLA-B genotypes influence NK cell function following stimulation with HLA-devoid cells

26 October 2017

1 reference

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Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells

26 October 2017

1 reference

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HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection

26 October 2017

1 reference

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Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation

26 October 2017

1 reference

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Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

26 October 2017

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Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

26 October 2017

1 reference

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IL-21 augments natural killer effector functions in chronically HIV-infected individuals

26 October 2017

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26 October 2017

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Up on the tightrope: natural killer cell activation and inhibition

26 October 2017

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Structural features of galectin-9 and galectin-1 that determine distinct T cell death pathways

26 October 2017

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26 October 2017

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Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells

26 October 2017

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Natural killer cells promote early CD8 T cell responses against cytomegalovirus

26 October 2017

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26 October 2017

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T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface

26 October 2017

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The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

26 October 2017

1 reference

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26 October 2017

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Characterization of CD56-/CD16+ natural killer (NK) cells: a highly dysfunctional NK subset expanded in HIV-infected viremic individuals

26 October 2017

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T Cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis

26 October 2017

1 reference

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NK cell and DC interactions

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750478

Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance

26 October 2017

1 reference

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Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750478

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

26 October 2017

1 reference

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Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.

26 October 2017

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Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma.

29 May 2018

1 reference

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17 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750478

HCV-specific T cells in HCV/HIV co-infection show elevated frequencies of dual Tim-3/PD-1 expression that correlate with liver disease progression

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750478

Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750478

Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750478

Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750478

CD107a as a functional marker for the identification of natural killer cell activity.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3750478

HIV Infection Deregulates Tim-3 Expression on Innate Cells

17 August 2018

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Crossref

https://api.crossref.org/works/10.1186%2F1742-4690-10-74

A combined genotype of KIR3DL1 high expressing alleles and HLA-B*57 is associated with a reduced risk of HIV infection

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23866914

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mind the gap: lack of association between KIR3DL1*004/HLA‐Bw4-induced natural killer cell function and protection from HIV infection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23866914

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1742-4690-10-74

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23866914%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23866914%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23866914%20AND%20SRC:MED&resulttype=core&format=json