Akt regulates nuclear/cytoplasmic localization of tuberin (Q42798601)

7 November 2017

title

Akt regulates nuclear/cytoplasmic localization of tuberin (English)

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7 November 2017

Rosner M

1

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7 November 2017

Freilinger A

series ordinal

2

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7 November 2017

Hengstschläger M

series ordinal

3

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7 November 2017

language of work or name

English

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publication date

24 July 2006

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7 November 2017

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7 November 2017

volume

26

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7 November 2017

issue

4

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7 November 2017

page(s)

521-531

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The TSC1 gene product, hamartin, negatively regulates cell proliferation

7 November 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Nuclear eukaryotic initiation factor 4E (eIF4E) colocalizes with splicing factors in speckles

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Ribosomal S6 kinase signaling and the control of translation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone beta receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Tuberous sclerosis gene 2 product modulates transcription mediated by steroid hormone receptor family members

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

TSC2 mediates cellular energy response to control cell growth and survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Cytoplasmic-nuclear shuttling of FKBP12-rapamycin-associated protein is involved in rapamycin-sensitive signaling and translation initiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Tuberous sclerosis: from tubers to mTOR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

A fraction of the mRNA 5' cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

The tuberous sclerosis 2 gene product can localize to nuclei in a phosphorylation-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Characterization of the cytosolic tuberin-hamartin complex. Tuberin is a cytosolic chaperone for hamartin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Tuberous sclerosis complex: from Drosophila to human disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Enhanced cardiomyocyte DNA synthesis during myocardial hypertrophy in mice expressing a modified TSC2 transgene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Akt regulates growth by directly phosphorylating Tsc2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Proteins interacting with the tuberous sclerosis gene products

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Tuberin binds p27 and negatively regulates its interaction with the SCF component Skp2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Cell size regulation by the human TSC tumor suppressor proteins depends on PI3K and FKBP38

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

A role of the tuberous sclerosis gene-2 product during neuronal differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Role of the tuberous sclerosis gene-2 product in cell cycle control. Loss of the tuberous sclerosis gene-2 induces quiescent cells to enter S phase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Inactivation of the cyclin-dependent kinase inhibitor p27 upon loss of the tuberous sclerosis complex gene-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Identification and characterization of the tuberous sclerosis gene on chromosome 16

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

TOR signaling in growth and metabolism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Predominant nuclear localization of mammalian target of rapamycin in normal and malignant cells in culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209812

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209812

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Dimensions Publication ID

7 November 2017

1049016724

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