Observation of unpaired substrate DNA in the flap endonuclease-1 active site. (Q42876251)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23975198%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Observation of unpaired substrate DNA in the flap endonuclease-1 active site (English)

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8 March 2020

2

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8 March 2020

L. David Finger

1

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8 March 2020

author name string

Amanda Beddows

3

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8 March 2020

Long Ma

4

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8 March 2020

Jack C Exell

5

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8 March 2020

Emma Jardine

6

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8 March 2020

Anita C Jones

7

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8 March 2020

Jane A Grasby

8

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8 March 2020

language of work or name

English

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publication date

23 August 2013

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8 March 2020

published in

Nucleic Acids Research

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8 March 2020

volume

41

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8 March 2020

issue

21

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8 March 2020

page(s)

9839-9847

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Creative Commons Attribution 3.0 Unported

8 March 2020

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

The wonders of flap endonucleases: structure, function, mechanism and regulation.

1 reference

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Elastic coupling between RNA degradation and unwinding by an exoribonuclease

27 May 2018

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Flap endonucleases pass 5'-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5'-ends

27 May 2018

1 reference

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Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases

27 May 2018

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Crystal structures of exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity

27 May 2018

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Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

27 May 2018

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Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily

27 May 2018

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DNA conformational changes at the primer-template junction regulate the fidelity of replication by DNA polymerase

27 May 2018

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Substrate recognition and catalysis by flap endonucleases and related enzymes

27 May 2018

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Time-resolved fluorescence studies of nucleotide flipping by restriction enzymes.

27 May 2018

1 reference

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The 3'-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834815

Spectroscopic studies of position-specific DNA "breathing" fluctuations at replication forks and primer-template junctions

27 May 2018

1 reference

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Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

27 May 2018

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Structure of the active subunit of the yeast exosome core, Rrp44: diverse modes of substrate recruitment in the RNase II nuclease family

27 May 2018

1 reference

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Crystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how flap endonuclease-1 family nucleases bind their substrates

27 May 2018

1 reference

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2-Aminopurine flipped into the active site of the adenine-specific DNA methyltransferase M.TaqI: crystal structures and time-resolved fluorescence

27 May 2018

1 reference

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Making and breaking nucleic acids: two-Mg2+-ion catalysis and substrate specificity

27 May 2018

1 reference

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Time-resolved fluorescence of 2-aminopurine as a probe of base flipping in M.HhaI-DNA complexes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834815

Structural basis for recruitment of human flap endonuclease 1 to PCNA

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834815

Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression

27 May 2018

1 reference

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Melting of a DNA helix terminus within the active site of a DNA polymerase

27 May 2018

1 reference

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Dynamics of mismatched base pairs in DNA.

27 May 2018

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Unwinding of primer-templates by archaeal family-B DNA polymerases in response to template-strand uracil

27 May 2018

1 reference

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Brønsted analysis and rate-limiting steps for the T5 flap endonuclease catalyzed hydrolysis of exonucleolytic substrates

16 August 2018

1 reference

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Three metal ions participate in the reaction catalyzed by T5 flap endonuclease.

16 August 2018

1 reference

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Fen1 mutations result in autoimmunity, chronic inflammation and cancers

16 August 2018

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Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA-bound complex.

16 August 2018

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Interstrand disulfide crosslinking of DNA bases supports a double nucleotide unpairing mechanism for flap endonucleases

16 August 2018

1 reference

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Branchpoint Expansion in a Fully Complementary Three-Way DNA Junction

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3834815

Effects of mutations on the partitioning of DNA substrates between the polymerase and 3'-5' exonuclease sites of DNA polymerase I (Klenow fragment)

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23975198

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKT737

1 reference

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8 March 2020

1 reference

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8 March 2020

PubMed publication ID

23975198

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23975198%20AND%20SRC:MED&resulttype=core&format=json