PCSK9-deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities. (Q43212730)

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15 January 2020

title

PCSK9-deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities (English)

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15 January 2020

8

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15 January 2020

Majambu Mbikay

1

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15 January 2020

Annik Prat

7

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15 January 2020

Michel Chrétien

9

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15 January 2020

3

Janice Mayne

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15 January 2020

2

Francine Sirois

1 reference

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15 January 2020

6

Thilina Dewpura

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15 January 2020

author name string

Gen-Sheng Wang

4

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15 January 2020

Andrew Chen

5

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15 January 2020

Fraser W Scott

10

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language of work or name

English

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publication date

16 December 2009

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15 January 2020

1 reference

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15 January 2020

volume

584

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15 January 2020

issue

4

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15 January 2020

page(s)

701-706

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The activation and physiological functions of the proprotein convertases

15 January 2020

cites work

1 reference

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The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation

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Proprotein convertase subtilisin/kexin type 9 (PCSK9): hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration

21 January 2018

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Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment

21 January 2018

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Effect of mutations in the PCSK9 gene on the cell surface LDL receptors

21 January 2018

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The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR

21 January 2018

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Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

21 January 2018

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Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype

21 January 2018

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Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver.

21 January 2018

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Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells

21 January 2018

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Fasting induces hyperlipidemia in mice overexpressing proprotein convertase subtilisin kexin type 9: lack of modulation of very-low-density lipoprotein hepatic output by the low-density lipoprotein receptor.

21 January 2018

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Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice

21 January 2018

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Low density lipoprotein can cause death of islet beta-cells by its cellular uptake and oxidative modification

21 January 2018

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Differences of pancreatic expression of 7B2 between C57BL/6J and C3H/HeJ mice and genetic polymorphisms at its locus (Sgne1).

21 January 2018

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Detection of exocytosis at individual pancreatic beta cells by amperometry at a chemically modified microelectrode.

21 January 2018

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Detection of specific polymerase chain reaction product by utilizing the 5'----3' exonuclease activity of Thermus aquaticus DNA polymerase

21 January 2018

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Cholesterol accumulation and diabetes in pancreatic beta-cell-specific SREBP-2 transgenic mice: a new model for lipotoxicity

21 January 2018

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Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment

21 January 2018

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Models of pancreatic regeneration in diabetes

21 January 2018

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Are the available experimental models of type 2 diabetes appropriate for a gender perspective?

21 January 2018

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Sex and depot differences in adipocyte insulin sensitivity and glucose metabolism

21 January 2018

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Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice

21 January 2018

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Mutations and polymorphisms in the proprotein convertase subtilisin kexin 9 (PCSK9) gene in cholesterol metabolism and disease.

21 January 2018

1 reference

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Characteristics of persons with marked hypocholesterolemia. A population-based study.

21 January 2018

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10.1016/J.FEBSLET.2009.12.018

21 January 2018

Identifiers

DOI

1 reference

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release_5xzz6ucae5e2zcqtpcgukpiu4e

15 January 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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