Regulation of IkappaB kinase (IKK) complex by IKKgamma-dependent phosphorylation of the T-loop and C terminus of IKKbeta (Q43526754)

24 November 2017

Regulation of IkappaB kinase (IKK) complex by IKKgamma-dependent phosphorylation of the T-loop and C terminus of IKKbeta (English)

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24 November 2017

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Beth Schomer-Miller

1

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24 November 2017

Tomoyasu Higashimoto

series ordinal

2

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24 November 2017

Yung-Kang Lee

series ordinal

3

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24 November 2017

Ebrahim Zandi

series ordinal

4

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24 November 2017

language of work or name

English

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publication date

5 April 2006

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Journal of Biological Chemistry

24 November 2017

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24 November 2017

281

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24 November 2017

22

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24 November 2017

15268-15276

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

24 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Missing pieces in the NF-kappaB puzzle

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M513793200

Structure, regulation and function of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

SCF(beta-TRCP) and phosphorylation dependent ubiquitinationof I kappa B alpha catalyzed by Ubc3 and Ubc4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Complete reconstitution of human IkappaB kinase (IKK) complex in yeast. Assessment of its stoichiometry and the role of IKKgamma on the complex activity in the absence of stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound Substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Limb and skin abnormalities in mice lacking IKKalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

A novel ubiquitin-like domain in IkappaB kinase beta is required for functional activity of the kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

Characterization of the Ikappa B-kinase NEMO binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513793200

21 January 2018

Identifiers

DOI

10.1074/JBC.M513793200

1 reference

24 November 2017

1 reference