Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain (Q43764263)

26 November 2017

Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain (English)

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26 November 2017

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26 November 2017

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R F Tyndale

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26 November 2017

K A Schoedel

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PubMed ID

11597571

26 November 2017

language of work or name

English

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publication date

1 October 2001

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26 November 2017

Biochemical Pharmacology

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26 November 2017

62

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26 November 2017

8

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26 November 2017

1025-1036

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Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins

26 November 2017

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Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substrate characteristics, the cytochrome b5 binding site and comparisons with CYP2B1 and CYP2B4

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Metabolism of carcinogenic N-nitroso-N-methylaniline by purified cytochromes P450 2B1 and P450 2B2.

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Inactivation of cytochromes P450 2B protects against cocaine-mediated toxicity in rat liver slices.

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Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes

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Nicotine metabolism by rat hepatic cytochrome P450s

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Comparative pharmacodynamics of CYP2B induction by DDT, DDE, and DDD in male rat liver and cultured rat hepatocytes.

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Cytochromes P-450 in rats: structures, functions, properties and relevant human forms

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Enhancement of hepatocarcinogenesis and induction of specific cytochrome P450-dependent monooxygenase activities by the barbiturates allobarbital, aprobarbital, pentobarbital, secobarbital and 5-phenyl- and 5-ethylbarbituric acids

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Tumor promotion by an anticonvulsant agent, phenytoin, in mouse liver: correlation with CYP2B induction

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Regional distribution of cytochrome P-450 in the rat brain: spectral quantitation and contribution of P-450b,e, and P-450c,d.

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Evidence for O-dealkylation of 7-pentoxyresorufin by cytochrome P450 2B1/2B2 isoenzymes in brain.

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Cytochrome P450-dependent biotransformation of drugs and other xenobiotic substrates in neural tissue

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Regional and cellular induction of nicotine-metabolizing CYP2B1 in rat brain by chronic nicotine treatment

7 January 2021

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The chronic administration of nicotine induces cytochrome P450 in rat brain.

7 January 2021

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Alcoholism, cigarette smoking, coffee drinking and extraversion

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Effects of ethanol on cigarette smoking by volunteers without histories of alcoholism

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Cigarette smoking by women: interactions with alcohol use.

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Common genetic vulnerability for nicotine and alcohol dependence in men

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Nicotine dependence and withdrawal in alcoholic and nonalcoholic ever-smokers

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Tolerance to and cross tolerance between ethanol and nicotine

7 January 2021

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Long-term ethanol treatment elicits changes in nicotinic receptor binding in only a few brain regions.

7 January 2021

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Chronic ethanol treatment decreases [3H]epibatidine and [3H]nicotine binding and differentially regulates mRNA levels of nicotinic acetylcholine receptor subunits expressed in M10 and SH-SY5Y neuroblastoma cells.

7 January 2021

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Ethanol-, fasting-, and acetone-inducible cytochromes P-450 in rat liver: regulation and characteristics of enzymes belonging to the IIB and IIE gene subfamilies.

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Receptor systems participating in nicotine-specific effects.

7 January 2021

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Chronic ethanol consumption: from neuroadaptation to neurodegeneration.

7 January 2021

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Distribution of cytochrome P450 activities towards alkoxyresorufin derivatives in rat brain regions, subcellular fractions and isolated cerebral microvessels

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Cross-reactivity of thirteen monoclonal antibodies with ten vaccinia cDNA expressed rat, mouse and human cytochrome P450s

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Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

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Liver triglyceride concentration and body protein metabolism in ethanol-treated rats: Effect of energy and nutrient supplementation

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Acetone-dependent regulation of cytochromes P4502E1 and P4502B1 in rat nasal mucosa

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Changes in Cytochromes P-450, 2E1, 2B1, and 4A, and Phospholipases A and C in the Intragastric Feeding Rat Model for Alcoholic Liver Disease: Relationship to Dietary Fats and Pathologic Liver Injury

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Additive cardiovascular effects of nicotine and ethanol

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Reassessment of cytochrome P450 2B2: catalytic specificity and identification of four active site residues

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The CYP2B2 phenobarbital response unit contains an accessory factor element and a putative glucocorticoid response element essential for conferring maximal phenobarbital responsiveness

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The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

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Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

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Ligand-dependent maintenance of ethanol-inducible cytochrome P-450 in primary rat hepatocyte cell cultures

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Ethanol suppresses growth hormone-mediated cellular responses in liver slices

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Different regulation of the expression of mouse hepatic cytochrome P450 2B enzymes by glucocorticoid and phenobarbital

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Insulin-mediated modulation of cytochrome P450 gene induction profiles in primary rat hepatocyte cultures

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A specific loss of growth hormone abolished sex-dependent expression of hepatic cytochrome P450 in dwarf rats: reversal of the profiles by growth hormone-treatment.

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Interactions of gender, growth hormone, and phenobarbital induction on murine Cyp2b expression.

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Induction of various cytochromes CYP2B, CYP2C and CYP3A by phenobarbitone in non-human primates

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7 January 2021

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Identifiers

DOI

10.1016/S0006-2952(01)00744-4

1 reference

26 November 2017

1 reference

PubMed ID

11597571