Ebola virus requires phosphatidylinositol (3,5) bisphosphate production for efficient viral entry (Q44105889)

29 November 2017

title

Ebola virus requires phosphatidylinositol (3,5) bisphosphate production for efficient viral entry (English)

1 reference

29 November 2017

main subject

Orthoebolavirus zairense

0 references

9

Gary Kobinger

1 reference

29 November 2017

10

Darwyn Kobasa

1 reference

29 November 2017

2

Anders Leung

1 reference

29 November 2017

4

Robert A Kozak

1 reference

29 November 2017

Shirley Qiu

1

1 reference

29 November 2017

Yuxia Bo

3

1 reference

29 November 2017

Sai Priya Anand

5

1 reference

29 November 2017

Corina Warkentin

6

1 reference

29 November 2017

Fabiola D R Salambanga

7

1 reference

29 November 2017

Jennifer Cui

8

1 reference

29 November 2017

Marceline Côté

11

1 reference

29 November 2017

language of work or name

English

0 references

publication date

11 October 2017

1 reference

29 November 2017

1 reference

29 November 2017

volume

513

1 reference

29 November 2017

page(s)

17-28

1 reference

Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and function

29 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Modular Detection of GFP-Labeled Proteins for Rapid Screening by Electron Microscopy in Cells and Organisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Phosphoinositides: tiny lipids with giant impact on cell regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Ebola virus: the role of macrophages and dendritic cells in the pathogenesis of Ebola hemorrhagic fever

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Salmonella modulates vesicular traffic by altering phosphoinositide metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Phosphatidylinositol-3,5-bisphosphate: no longer the poor PIP2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

PIKfyve-ArPIKfyve-Sac3 core complex: contact sites and their consequence for Sac3 phosphatase activity and endocytic membrane homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

ArPIKfyve regulates Sac3 protein abundance and turnover: disruption of the mechanism by Sac3I41T mutation causing Charcot-Marie-Tooth 4J disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

The Protein Complex of Neurodegeneration-related Phosphoinositide Phosphatase Sac3 and ArPIKfyve Binds the Lewy Body-associated Synphilin-1, Preventing Its Aggregation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Covalent modifications of the ebola virus glycoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Convergent regulation of the lysosomal two-pore channel-2 by Mg²⁺, NAADP, PI(3,5)P₂ and multiple protein kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P(2) in yeast and mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Phosphatidylinositol 3,5-bisphosphate: regulation of cellular events in space and time

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Host cell factors and functions involved in vesicular stomatitis virus entry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Inhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

PIKfyve inhibition interferes with phagosome and endosome maturation in macrophages.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

AMP-activated protein kinase is required for the macropinocytic internalization of ebolavirus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Ebolavirus glycoprotein structure and mechanism of entry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-A resolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Expression of Ebolavirus glycoprotein on the target cells enhances viral entry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Involvement of cellular proteins in Junin arenavirus entry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Ebola virus entry requires the host-programmed recognition of an intracellular receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Ebola virus and severe acute respiratory syndrome coronavirus display late cell entry kinetics: evidence that transport to NPC1+ endolysosomes is a rate-defining step

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

A spatio-temporal analysis of matrix protein and nucleocapsid trafficking during vesicular stomatitis virus uncoating

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Phosphoinositide phosphatase Sac3 regulates the cell surface expression of scavenger receptor A and formation of lipid droplets in macrophages.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

The phosphatidylinositol-3-phosphate 5-kinase inhibitor apilimod blocks filoviral entry and infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Ebola virus VP40 drives the formation of virus-like filamentous particles along with GP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

FIG4 variants in central European patients with amyotrophic lateral sclerosis: a whole-exome and targeted sequencing study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Vaccinia Virus Infection Requires Maturation of Macropinosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Cellular Entry of Ebola Virus Involves Uptake by a Macropinocytosis-Like Mechanism and Subsequent Trafficking through Early and Late Endosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Ebola virus. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Improved vectors and genome-wide libraries for CRISPR screening

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Multiple cationic amphiphiles induce a Niemann-Pick C phenotype and inhibit Ebola virus entry and infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Ebolavirus Glycoprotein Directs Fusion through NPC1+ Endolysosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Rapid and efficient one-step generation of paired gRNA CRISPR-Cas9 libraries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Genetic screens in human cells using the CRISPR-Cas9 system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Intersubunit interactions modulate pH-induced activation of membrane fusion by the Junin virus envelope glycoprotein GPC.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2017.09.028

10.1016/J.VIROL.2017.09.028

7 January 2021

Identifiers

DOI

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/buj3fk3k5zhbpkyh5nc5vz7l34

mapped directly with Wikidata item

30 July 2022

based on heuristic

Fatcat ID

release_buj3fk3k5zhbpkyh5nc5vz7l34

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/buj3fk3k5zhbpkyh5nc5vz7l34

mapped directly with Wikidata item

30 July 2022

based on heuristic

https://api.fatcat.wiki/v0/release/buj3fk3k5zhbpkyh5nc5vz7l34

1 reference