Proteasomal activity modulates TGF-ss signaling in a gene-specific manner (Q44130958)

30 November 2017

Proteasomal activity modulates TGF-ss signaling in a gene-specific manner (English)

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30 November 2017

Fan Zhang

1

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30 November 2017

Mia Mönkkönen

series ordinal

2

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30 November 2017

Stina Roth

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3

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30 November 2017

Marikki Laiho

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4

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30 November 2017

language of work or name

English

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publication date

1 September 2002

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30 November 2017

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30 November 2017

527

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30 November 2017

1-3

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30 November 2017

58-62

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TGFbeta signaling in growth control, cancer, and heritable disorders

30 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

TGF-beta signaling in tumor suppression and cancer progression

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Ubiquitin-dependent degradation of TGF-beta-activated smad2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Ski/Sno and TGF-beta signaling.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Hepatocyte growth factor releases mink epithelial cells from transforming growth factor beta1-induced growth arrest by restoring Cdk6 expression and cyclin E-associated Cdk2 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Ectopic expression of Cdk6 circumvents transforming growth factor-beta mediated growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

c-myc is a downstream target of the Smad pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Early gene responses to transforming growth factor-beta in cells lacking growth-suppressive RB function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

Functional characterization of transforming growth factor beta signaling in Smad2- and Smad3-deficient fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

The L45 loop in type I receptors for TGF-beta family members is a critical determinant in specifying Smad isoform activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903163-0

10.1016/S0014-5793(02)03163-0

7 January 2021

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DOI

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release_r573y64bbvfatgr7sthvw3zrvm

30 November 2017

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Fatcat

https://api.fatcat.wiki/v0/release/r573y64bbvfatgr7sthvw3zrvm

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24 November 2022

based on heuristic

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