MDM2/MDMX inhibitor peptide: WO2008106507. (Q44435579)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19441944%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

MDM2/MDMX inhibitor peptide: WO2008106507 (English)

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1

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28 January 2020

author name string

Roberto Pellicciari

series ordinal

2

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28 January 2020

language of work or name

English

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publication date

1 May 2009

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Expert Opinion on Therapeutic Patents

28 January 2020

published in

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volume

19

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issue

5

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page(s)

721-726

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p53: a guide to apoptosis

28 January 2020

cites work

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Mdm2 and Mdm4 loss regulates distinct p53 activities

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Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.

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p53 in health and disease

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MDM2 and MDM4: p53 regulators as targets in anticancer therapy

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Targeting MDM2 and MDMX in retinoblastoma

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Inactivation of the p53 pathway in retinoblastoma.

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MDM2 inhibitors for cancer therapy

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

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MDMX overexpression prevents p53 activation by the MDM2 inhibitor Nutlin.

21 January 2018

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Distinct roles of MDMX in the regulation of p53 response to ribosomal stress

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MDMX: from bench to bedside

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Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX

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Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.

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Molecular characterization of the hdm2-p53 interaction

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Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

21 January 2018

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Molecular basis for the inhibition of p53 by Mdmx

21 January 2018

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Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain

21 January 2018

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A simple method for displaying the hydropathic character of a protein

21 January 2018

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The characterization of amino acid sequences in proteins by statistical methods

21 January 2018

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Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

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Small-molecule inhibitors of the p53 suppressor HDM2: have protein-protein interactions come of age as drug targets?

21 January 2018

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

21 January 2018

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The MDM2 inhibitor Nutlins as an innovative therapeutic tool for the treatment of haematological malignancies

21 January 2018

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Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

21 January 2018

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Protein Identification and Analysis Tools on the ExPASy Server

21 January 2018

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10.1517/13543770902755137

21 January 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19441944%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

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