Arsenite induces delayed mutagenesis and transformation in human osteosarcoma cells at extremely low concentrations (Q44475735)

3 December 2017

title

Arsenite induces delayed mutagenesis and transformation in human osteosarcoma cells at extremely low concentrations (English)

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3 December 2017

Kanae Mure

1

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3 December 2017

Ahmed N Uddin

2

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3 December 2017

Laura C Lopez

3

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3 December 2017

Miroslav Styblo

4

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3 December 2017

Toby G Rossman

5

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3 December 2017

publication date

1 January 2003

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Environmental and Molecular Mutagenesis

3 December 2017

published in

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3 December 2017

volume

41

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3 December 2017

issue

5

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3 December 2017

page(s)

322-331

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Chemical carcinogens transform BHK cells by inducing a recessive mutation

3 December 2017

cites work

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Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakage

21 January 2018

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Modeling and measurement of the spontaneous mutation rate in mammalian cells

21 January 2018

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Influence of nutrient intake on blood lead levels of young children at risk for lead poisoning

21 January 2018

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Effects of arsenite on p53, p21 and cyclin D expression in normal human fibroblasts -- a possible mechanism for arsenite's comutagenicity

21 January 2018

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Ras signals to the cell cycle machinery via multiple pathways to induce anchorage-independent growth

21 January 2018

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Arsenic induces and enhances rat hepatic metallothionein production in vivo

21 January 2018

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7 January 2021

Stimulation of reactive oxygen, but not reactive nitrogen species, in vascular endothelial cells exposed to low levels of arsenite

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7 January 2021

Low levels of arsenic trioxide stimulate proliferative signals in primary vascular cells without activating stress effector pathways

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7 January 2021

Mechanisms of arsenic-induced cell transformation

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7 January 2021

Nitric oxide is involved in arsenite inhibition of pyrimidine dimer excision

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7 January 2021

Gene amplification in methotrexate-resistant mouse cells. V. Intact amplified units can be transferred to and amplified in methotrexate-sensitive mouse L cells.

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7 January 2021

Association of c-myc overexpression and hyperproliferation with arsenite-induced malignant transformation

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7 January 2021

Arsenic inhibition of telomerase transcription leads to genetic instability

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7 January 2021

Time dependence of accumulation and binding of inorganic and organic arsenic species in rabbit erythrocytes

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7 January 2021

Determination of trivalent methylated arsenicals in biological matrices.

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7 January 2021

Stress proteins induced by arsenic.

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7 January 2021

The role of AP-1, NF-kappaB and ROS/NOS in skin carcinogenesis: the JB6 model is predictive

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7 January 2021

Hydrogen peroxide induced mutations at the HPRT locus in primary human T-lymphocytes

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7 January 2021

Suppression of spontaneous and hydrogen peroxide-induced mutagenesis by the antioxidant ascorbate in mismatch repair-deficient human colon cancer cells

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7 January 2021

Induction of chromatid breaks and tetraploidy in Chinese hamster ovary cells by treatment with sodium arsenite during the G2 phase

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7 January 2021

Calcium-dependent nitric oxide production is involved in arsenite-induced micronuclei

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7 January 2021

Telomere dysfunction increases mutation rate and genomic instability

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7 January 2021

Mutagenicity of arsenic in mammalian cells: role of reactive oxygen species

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7 January 2021

Arsenic toxicity is enzyme specific and its affects on ligation are not caused by the direct inhibition of DNA repair enzymes

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7 January 2021

Requirement of Erk, but not JNK, for arsenite-induced cell transformation

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7 January 2021

The dual role model for p53 in maintaining genomic integrity

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7 January 2021

The role of DNA methylation in mammalian epigenetics

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7 January 2021

The relationship between tumorigenicity, growth in agar and fibrinolytic activity in a line of human osteosarcoma cells

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7 January 2021

Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite

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7 January 2021

DNA methylation, heterochromatin and epigenetic carcinogens

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7 January 2021

Comparison of arsenic-induced cell transformation, cytotoxicity, mutation and cytogenetic effects in Syrian hamster embryo cells in culture.

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7 January 2021

Induction of gene amplification by arsenic

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7 January 2021

Nickel chloride inhibits the DNA repair of UV-treated but not methyl methanesulfonate-treated Chinese hamster ovary cells

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7 January 2021

Differential effects of luminol, nickel, and arsenite on the rejoining of ultraviolet light and alkylation-induced DNA breaks

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7 January 2021

Comutagenesis of sodium arsenite with ultraviolet radiation in Chinese hamster V79 cells

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7 January 2021

Transformation of human osteoblasts to anchorage-independent growth by insoluble nickel particles

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7 January 2021

Methylarsenicals and arsinothiols are potent inhibitors of mouse liver thioredoxin reductase

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7 January 2021

Regulation of expression of the human heme oxygenase-1 gene in transfected chick embryo liver cell cultures

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7 January 2021

Arsenite stimulates poly(ADP-ribosylation) by generation of nitric oxide

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7 January 2021

Arsenic alters cytosine methylation patterns of the promoter of the tumor suppressor gene p53 in human lung cells: a model for a mechanism of carcinogenesis

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7 January 2021

Methylated trivalent arsenic species are genotoxic

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7 January 2021

Polymerase chain reaction-based deletion analysis of spontaneous and arsenite-enhanced gpt mutants in CHO-AS52 cells

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7 January 2021

Transformation of human osteoblast cells to the tumorigenic phenotype by depleted uranium-uranyl chloride

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7 January 2021

Relative genotoxic potency of arsenic and its methylated metabolites

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7 January 2021

Monomethylarsonous acid (MMA(III)) is more toxic than arsenite in Chang human hepatocytes

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7 January 2021

Transformation of non-tumorigenic osteoblast-like human osteosarcoma cells by hexavalent chromates: alteration of morphology, induction of anchorage-independence and proteolytic function

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7 January 2021

Preparation and purification of 74As-labeled arsenate and arsenite for use in biological experiments

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7 January 2021

Transformation of human cells in culture by N-methyl-N'-nitro-N-nitrosoguanidine

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7 January 2021

Role of DNA methylation in the regulation of cell function

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7 January 2021

Effect of metals on mutagenesis and DNA repair

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7 January 2021

Differential susceptibility to carcinogen-induced amplification of SV40 and dhfr sequences in SV40-transformed human keratinocytes

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7 January 2021

Absence of arsenite mutagenicity in E coli and Chinese hamster cells.

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7 January 2021

Human cells lack the inducible tolerance to arsenite seen in hamster cells

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7 January 2021

Presence of telomerase activity in different musculoskeletal tumor histotypes and correlation with aggressiveness

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7 January 2021

Alternative lengthening of telomeres is associated with chromosomal instability in osteosarcomas

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7 January 2021

Reactions of arsenic(III) and arsenic(V) species with glutathione

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7 January 2021

Signaling networks that link cell proliferation and cell fate

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7 January 2021

Comparative in vitro methylation of trivalent and pentavalent arsenicals

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7 January 2021

Comparative inhibition of yeast glutathione reductase by arsenicals and arsenothiols

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7 January 2021

Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells

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7 January 2021

Transformation by inorganic arsenic compounds of normal Syrian hamster embryo cells into a neoplastic state in which they become anchorage-independent and cause tumors in newborn hamsters

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7 January 2021

The cellular metabolism and systemic toxicity of arsenic

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7 January 2021

Effects and dose--response relationships of skin cancer and blackfoot disease with arsenic

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7 January 2021

Genetic alterations during colorectal-tumor development

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7 January 2021

Arsenite induces oxidative DNA adducts and DNA-protein cross-links in mammalian cells

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7 January 2021

Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression

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7 January 2021

Identifiers

DOI

10.1002/EM.10164

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3 December 2017

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