pVHL-independent ubiquitination of HIF1alpha and its stabilization by cobalt ion. (Q44480238)

3 December 2017

pVHL-independent ubiquitination of HIF1alpha and its stabilization by cobalt ion. (English)

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3 December 2017

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protein ubiquitination

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Koichi Kanaya

1

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PubMed ID

12810083

3 December 2017

Tetsu Kamitani

series ordinal

2

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PubMed ID

12810083

3 December 2017

language of work or name

English

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publication date

1 July 2003

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Biochemical and Biophysical Research Communications

3 December 2017

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3 December 2017

306

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3 December 2017

3

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3 December 2017

750-755

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Identification of the von Hippel-Lindau (VHL) gene. Its role in renal cancer

3 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Tumour suppression by the human von Hippel-Lindau gene product

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Inhibition of transcription elongation by the VHL tumor suppressor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Ubiquitin-like proteins: new wines in new bottles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Many vessels, faulty gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Signal transduction. How do cells sense oxygen?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

The von Hippel-Lindau tumor suppressor gene product promotes, but is not essential for, NEDD8 conjugation to cullin-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Identification of NEDD8-conjugation site in human cullin-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

A dominant-negative UBC12 mutant sequesters NEDD8 and inhibits NEDD8 conjugation in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Mutations of the VHL tumour suppressor gene in renal carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Proteasome inhibitors: valuable new tools for cell biologists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Surface topography of histidine residues: a facile probe by immobilized metal ion affinity chromatography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Signal transduction to hypoxia-inducible factor 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

Oxygen-dependent and -independent regulation of HIF-1alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2803%2901041-6

10.1016/S0006-291X(03)01041-6

7 January 2021

Identifiers

DOI

1 reference

3 December 2017

1 reference

PubMed ID

12810083