Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells (Q44762625)

6 December 2017

Smac/DIABLO selectively reduces the levels of c-IAP1 and c-IAP2 but not that of XIAP and livin in HeLa cells (English)

1 reference

6 December 2017

Qi-Heng Yang

1

1 reference

PubMed ID

14960576

6 December 2017

Chunying Du

series ordinal

2

1 reference

PubMed ID

14960576

6 December 2017

language of work or name

English

0 references

publication date

11 February 2004

1 reference

Journal of Biological Chemistry

6 December 2017

1 reference

6 December 2017

279

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6 December 2017

17

1 reference

6 December 2017

16963-16970

1 reference

The inhibitors of apoptosis: there is more to life than Bcl2.

6 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Drosophila sickle is a novel grim-reaper cell death activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, grim, and hid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Regulation of apoptosis: the ubiquitous way

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

The Drosophila DIAP1 protein is required to prevent accumulation of a continuously generated, processed form of the apical caspase DRONC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Reaper is regulated by IAP-mediated ubiquitination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Unlike Diablo/smac, Grim promotes global ubiquitination and specific degradation of X chromosome-linked inhibitor of apoptosis (XIAP) and neither cause apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Smac3, a Novel Smac/DIABLO Splicing Variant, Attenuates the Stability and Apoptosis-inhibiting Activity of X-linked Inhibitor of Apoptosis Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

IAP proteins: blocking the road to death's door

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Ubiquitin fusion technique and its descendants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Linearization of the Bradford protein assay increases its sensitivity: theoretical and experimental studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

A novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLO

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Monoubiquitination and cellular distribution of XIAP in neurons after traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Mechanisms underlying ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Herpes simplex virus type 1 immediate-early protein ICP0 and is isolated RING finger domain act as ubiquitin E3 ligases in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Herpes simplex virus 1-infected cell protein 0 contains two E3 ubiquitin ligase sites specific for different E2 ubiquitin-conjugating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Identification of a family of closely related human ubiquitin conjugating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401253200

21 January 2018

Identifiers

DOI

10.1074/JBC.M401253200

1 reference

6 December 2017

1 reference

PubMed ID

14960576