Molecular cross-talk between MEK1/2 and mTOR signaling during recovery of 293 cells from hypertonic stress (Q45005978)

8 December 2017

Molecular cross-talk between MEK1/2 and mTOR signaling during recovery of 293 cells from hypertonic stress (English)

1 reference

8 December 2017

1 reference

Susanne Naegele

1

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PubMed ID

15292274

8 December 2017

Simon J Morley

series ordinal

2

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PubMed ID

15292274

8 December 2017

language of work or name

English

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publication date

3 August 2004

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Journal of Biological Chemistry

8 December 2017

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8 December 2017

279

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8 December 2017

44

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8 December 2017

46023-46034

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eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

8 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Cocrystal structure of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Control of the translational machinery in mammalian cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M404945200

Eukaryotic translation initiation factors and regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Starting the protein synthesis machine: eukaryotic translation initiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Features in the N and C termini of the MAPK-interacting kinase Mnk1 mediate its nucleocytoplasmic shuttling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Phosphorylation of the cap-binding protein eIF4E by the MAPK-activated protein kinase Mnk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Tumour suppressors hamartin and tuberin: intracellular signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Inactivation of the tuberous sclerosis complex-1 and -2 gene products occurs by phosphoinositide 3-kinase/Akt-dependent and -independent phosphorylation of tuberin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

TSC2: filling the GAP in the mTOR signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Rhebbing up mTOR: New Insights on TSC1 and TSC2, and the Pathogenesis of Tuberous Sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Cleavage of eukaryotic translation initiation factor 4G by exogenously added hybrid proteins containing poliovirus 2Apro in HeLa cells: effects on gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Phosphorylation of eukaryotic initiation factor (eIF) 4E is not required for de novo protein synthesis following recovery from hypertonic stress in human kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Involvement of stress-activated protein kinase and p38/RK mitogen-activated protein kinase signaling pathways in the enhanced phosphorylation of initiation factor 4E in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Phosphorylation of initiation factor 4E is resistant to SB203580 in cells expressing a drug-resistant mutant of stress-activated protein kinase 2a/p38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Changes in integrity and association of eukaryotic protein synthesis initiation factors during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Targeting mTOR signaling for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Specificity and mechanism of action of some commonly used protein kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Cell-cycle arrest by PD184352 requires inhibition of extracellular signal-regulated kinases (ERK) 1/2 but not ERK5/BMK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Regulation of the phosphorylation of elongation factor 2 by MEK-dependent signalling in adult rat cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Regulation of mammalian translation factors by nutrients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Cross-talk between the ERK and p70 S6 kinase (S6K) signaling pathways. MEK-dependent activation of S6K2 in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Molecular crosstalk between p70S6k and MAPK cell signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

Regulation of TSC2 by 14-3-3 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404945200

21 January 2018

Identifiers

DOI

10.1074/JBC.M404945200

1 reference

8 December 2017

1 reference

PubMed ID

15292274