MiR-26a enhances the radiosensitivity of glioblastoma multiforme cells through targeting of ataxia-telangiectasia mutated (Q45012413)

8 December 2017

MiR-26a enhances the radiosensitivity of glioblastoma multiforme cells through targeting of ataxia-telangiectasia mutated (English)

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8 December 2017

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Pin Guo

1

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8 December 2017

Jin Lan

2

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8 December 2017

Jianwei Ge

3

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8 December 2017

Quanmin Nie

4

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8 December 2017

Liemei Guo

5

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8 December 2017

Yongming Qiu

6

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8 December 2017

Qing Mao

7

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8 December 2017

language of work or name

English

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publication date

5 November 2013

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Experimental Cell Research

8 December 2017

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8 December 2017

320

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8 December 2017

200-208

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8 December 2017

2

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Malignant astrocytic glioma: genetics, biology, and paths to treatment

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Phosphatase and tensin homologue deficiency in glioblastoma confers resistance to radiation and temozolomide that is reversed by the protease inhibitor nelfinavir

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Revival of the abandoned therapeutic wortmannin by nanoparticle drug delivery.

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Counteracting tumor radioresistance by targeting DNA repair

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DNA repair after irradiation in glioma cells and normal human astrocytes

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Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells

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DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells.

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Double strand break repair by homologous recombination is regulated by cell cycle-independent signaling via ATM in human glioma cells

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Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

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DNA damage responses: mechanisms and roles in human disease: 2007 G.H.A. Clowes Memorial Award Lecture

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ATM activation and DNA damage response

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ATM phosphorylates histone H2AX in response to DNA double-strand breaks

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Phosphatases in the cellular response to DNA damage.

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H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy.

7 January 2021

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Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

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ATM: from gene to function

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Atm-deficient mice: a paradigm of ataxia telangiectasia

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DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis

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Absence of mutations in the ATM gene in breast cancer patients with severe responses to radiotherapy

7 January 2021

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Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia

7 January 2021

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Expression of ATM protein and its relationship with p53 in pancreatic carcinoma with tissue array.

7 January 2021

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MicroRNAs: genomics, biogenesis, mechanism, and function

7 January 2021

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MicroRNAs: target recognition and regulatory functions

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Transcriptional modulation of micro-RNA in human cells differing in radiation sensitivity

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MiR-181a confers resistance of cervical cancer to radiation therapy through targeting the pro-apoptotic PRKCD gene

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Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma

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Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras

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Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation

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Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship

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Serine/threonine protein phosphatase 6 modulates the radiation sensitivity of glioblastoma

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Characteristics of gamma-H2AX foci at DNA double-strand breaks sites

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Role of cell cycle in mediating sensitivity to radiotherapy

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Down-regulation of microRNA-26a promotes mouse hepatocyte proliferation during liver regeneration

7 January 2021

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MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S transition by activating the pRb protein

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miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase.

7 January 2021

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ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

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ATM is a target for positive regulation by E2F-1.

7 January 2021

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Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line

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The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

7 January 2021

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Tying the loose ends together in DNA double strand break repair with 53BP1.

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10.1016/J.YEXCR.2013.10.020

7 January 2021

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DOI

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8 December 2017

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