Human Bloom protein stimulates flap endonuclease 1 activity by resolving DNA secondary structure (Q45173725)

10 December 2017

Human Bloom protein stimulates flap endonuclease 1 activity by resolving DNA secondary structure (English)

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10 December 2017

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Wensheng Wang

1

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PubMed ID

15579905

10 December 2017

Robert A Bambara

series ordinal

2

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PubMed ID

15579905

10 December 2017

language of work or name

English

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publication date

4 December 2004

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Journal of Biological Chemistry

10 December 2017

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10 December 2017

280

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10 December 2017

7

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10 December 2017

5391-5399

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Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair

10 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Flap endonuclease homologs in archaebacteria exist as independent proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Deoxyribonuclease IV: a new exonuclease from mammalian tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Enzymes and reactions at the eukaryotic DNA replication fork

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

What we could do now: molecular pathology of colorectal cancer

21 January 2018

1 reference

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Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Vertebrate cells lacking FEN-1 endonuclease are viable but hypersensitive to methylating agents and H2O2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Characterization of a mutant strain of Saccharomyces cerevisiae with a deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Functional analysis of human FEN1 in Saccharomyces cerevisiae and its role in genome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Flap endonuclease 1: a central component of DNA metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Novel function of Rad27 (FEN-1) in restricting short-sequence recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

A role for FEN-1 in nonhomologous DNA end joining: the order of strand annealing and nucleolytic processing events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeast dna2 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

The Bloom's syndrome gene product is homologous to RecQ helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Cancer predisposition caused by elevated mitotic recombination in Bloom mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M412359200

Possible association of BLM in decreasing DNA double strand breaks during DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

The function of Xenopus Bloom's syndrome protein homolog (xBLM) in DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

A retarded rate of DNA chain growth in Bloom's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

The Bloom's syndrome gene product promotes branch migration of holliday junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Telomere and ribosomal DNA repeats are chromosomal targets of the bloom syndrome DNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

DNA2 encodes a DNA helicase essential for replication of eukaryotic chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

The nuclease activity of the yeast DNA2 protein, which is related to the RecB-like nucleases, is essential in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Stimulation of flap endonuclease-1 by the Bloom's syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

The DNA helicase activity of BLM is necessary for the correction of the genomic instability of bloom syndrome cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

The Bloom's syndrome gene product is a 3'-5' DNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Effect of flap modifications on human FEN1 cleavage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Analysis of human flap endonuclease 1 mutants reveals a mechanism to prevent triplet repeat expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Mapping the polarity of changes that occur in interrupted CAG repeat tracts in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

DNA ligase I competes with FEN1 to expand repetitive DNA sequences in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Systematic genetic analysis with ordered arrays of yeast deletion mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Links between replication and recombination in Saccharomyces cerevisiae: a hypersensitive requirement for homologous recombination in the absence of Rad27 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

On the roles of Saccharomyces cerevisiae Dna2p and Flap endonuclease 1 in Okazaki fragment processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

Gene 5.5 protein of bacteriophage T7 inhibits the nucleoid protein H-NS of Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412359200

21 January 2018

Identifiers

DOI

10.1074/JBC.M412359200

1 reference

10 December 2017

1 reference

PubMed ID

15579905