High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NFkappaB. (Q45288341)

11 December 2017

title

High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NFkappaB. (English)

1 reference

11 December 2017

H Elouil

1

1 reference

11 December 2017

A K Cardozo

2

1 reference

11 December 2017

D L Eizirik

3

1 reference

11 December 2017

J C Henquin

4

1 reference

11 December 2017

J C Jonas

5

1 reference

11 December 2017

publication date

1 March 2005

1 reference

11 December 2017

1 reference

11 December 2017

volume

48

1 reference

11 December 2017

issue

3

1 reference

11 December 2017

page(s)

496-505

1 reference

Involvement of protein kinase C beta 2 in c-myc induction by high glucose in pancreatic beta-cells

11 December 2017

cites work

1 reference

12 December 2020

Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?

1 reference

12 December 2020

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis

1 reference

12 December 2020

High glucose stimulates early response gene c-Myc expression in rat pancreatic beta cells

1 reference

12 December 2020

U.K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. U.K. Prospective Diabetes Study Group

1 reference

12 December 2020

Culture of adult human islet preparations with hepatocyte growth factor and 804G matrix is mitogenic for duct cells but not for beta-cells

1 reference

12 December 2020

Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines

1 reference

12 December 2020

Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes

1 reference

12 December 2020

Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress

1 reference

12 December 2020

The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes

1 reference

12 December 2020

Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia

1 reference

12 December 2020

Inhibition of TNF-alpha production by pentoxifylline does not prevent endotoxin-induced decrease in serum IGF-I.

1 reference

12 December 2020

Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB

1 reference

12 December 2020

Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection

1 reference

12 December 2020

Prolonged culture in low glucose induces apoptosis of rat pancreatic beta-cells through induction of c-myc.

1 reference

12 December 2020

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

1 reference

12 December 2020

Cellular composition of the human diabetic pancreas

1 reference

12 December 2020

Activation of transcription factors by drugs inducing oxidative stress in rat liver.

1 reference

12 December 2020

Glucose and tolbutamide induce apoptosis in pancreatic beta-cells. A process dependent on intracellular Ca2+ concentration

1 reference

12 December 2020

Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis

1 reference

12 December 2020

Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes

1 reference

12 December 2020

A role for glutathione peroxidase in protecting pancreatic beta cells against oxidative stress in a model of glucose toxicity

1 reference

12 December 2020

Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells

1 reference

12 December 2020

Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays

1 reference

12 December 2020

Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation

1 reference

12 December 2020

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

1 reference

12 December 2020

Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries.

1 reference

12 December 2020

Dose-dependent cysteine-mediated protection of insulin-producing cells from damage by hydrogen peroxide

1 reference

12 December 2020

Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

1 reference

12 December 2020

Cytokine induction of Fas gene expression in insulin-producing cells requires the transcription factors NF-kappaB and C/EBP.

1 reference

12 December 2020

Increase in insulin response after treatment of overt maturity-onset diabetes is independent of the mode of treatment.

1 reference

12 December 2020

NF-kappaB is required for cytokine-induced manganese superoxide dismutase expression in insulin-producing cells

1 reference

12 December 2020

Product differentiation by analysis of DNA melting curves during the polymerase chain reaction

1 reference

12 December 2020

Pancreatic beta-cell loss and preservation in type 2 diabetes

1 reference

12 December 2020

Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity

1 reference

12 December 2020

A protective role for heme oxygenase expression in pancreatic islets exposed to interleukin-1beta

1 reference

12 December 2020

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

12 December 2020

Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays

1 reference

12 December 2020

Glycation-dependent, reactive oxygen species-mediated suppression of the insulin gene promoter activity in HIT cells

1 reference

12 December 2020

Determination of total serum insulin (IRI) in insulin-treated diabetic patients

1 reference

12 December 2020

Heme oxygenase-1 induction in islet cells results in protection from apoptosis and improved in vivo function after transplantation

1 reference

12 December 2020

Effects of chronically elevated glucose levels on the functional properties of rat pancreatic beta-cells

1 reference

12 December 2020

Heme oxygenase-1 protects pancreatic beta cells from apoptosis caused by various stimuli

1 reference

12 December 2020

A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells

1 reference

12 December 2020

Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in ty

1 reference

12 December 2020

Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress.

1 reference

12 December 2020

Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes

1 reference

12 December 2020

Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression

1 reference

12 December 2020

Haeme-oxygenase 1 expression in rat pancreatic beta cells is stimulated by supraphysiological glucose concentrations and by cyclic AMP.

1 reference

12 December 2020

Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity

1 reference

12 December 2020

Glucotoxicity and beta-cell failure in type 2 diabetes mellitus

1 reference

12 December 2020

Increased glucose sensitivity of both triggering and amplifying pathways of insulin secretion in rat islets cultured for 1 wk in high glucose

1 reference

12 December 2020

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

1 reference

12 December 2020

Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants

1 reference

12 December 2020

Signaling through the p38 and p42/44 mitogen-activated families of protein kinases in pancreatic beta-cell proliferation.

1 reference

12 December 2020

Evolution of β-Cell Dysfunction in the Male Zucker Diabetic Fatty Rat

1 reference

12 December 2020

AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase

1 reference

12 December 2020

10.1007/S00125-004-1664-4

Identifiers

DOI

1 reference

Dimensions Publication ID

11 December 2017

1042715158

0 references

1 reference