Glutathione prevents free fatty acids-induced oxidative stress and apoptosis in human brain vascular endothelial cells through Akt pathway (Q45375833)

13 December 2017

Glutathione prevents free fatty acids-induced oxidative stress and apoptosis in human brain vascular endothelial cells through Akt pathway (English)

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13 December 2017

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Hou-Guang Zhou

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493493&resulttype=core&format=json

14 May 2020

Ling Liu

2

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14 May 2020

Yu Zhang

3

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14 May 2020

Yan-Yan Huang

4

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Ying-Hong Tao

5

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14 May 2020

Shuo Zhang

6

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Jing-Jing Su

7

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14 May 2020

Yu-Ping Tang

8

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14 May 2020

Zhuang-Li Guo

9

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Ren-Ming Hu

10

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Qiang Dong

11

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publication date

1 April 2013

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CNS Neuroscience & Therapeutics

13 December 2017

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14 May 2020

volume

19

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issue

4

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14 May 2020

page(s)

252-261

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Cardiovascular disease in diabetes: where does glucose fit in?

14 May 2020

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Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes

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Vascular function, insulin resistance and fatty acids

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Oxidative stress and apoptosis of human brain microvascular endothelial cells induced by free fatty acids.

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Alpha-synuclein, lipids and Parkinson's disease

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Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice

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Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells

21 January 2018

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2,7-Dihydrodichlorofluorescein diacetate as a fluorescent marker for peroxynitrite formation

21 January 2018

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Measurement of membrane permeability and permeability transition of mitochondria

21 January 2018

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Hyperglycemia alters PI3k and Akt signaling and leads to endothelial cell proliferative dysfunction

21 January 2018

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Free radical production and changes in superoxide dismutases associated with hypoxia/reoxygenation-induced apoptosis of embryonic rat forebrain neurons in culture.

21 January 2018

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Reactive oxygen radicals in signaling and damage in the ischemic brain

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Reactive Oxygen Radicals and Pathogenesis of Neuronal Death After Cerebral Ischemia

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To reviews on physiological and pathological roles of cell death

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Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation

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S-nitrosylation of proteins: a new insight into endothelial cell function regulated by eNOS-derived NO.

21 January 2018

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Mitochondria: a target for neuroprotective interventions in cerebral ischemia-reperfusion

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Redox-active quinones and ascorbate: an innovative cancer therapy that exploits the vulnerability of cancer cells to oxidative stress

21 January 2018

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Reactive oxygen species as signaling molecules in cardiovascular differentiation of embryonic stem cells and tumor-induced angiogenesis

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Mitochondrial permeability transition: a common pathway to necrosis and apoptosis

21 January 2018

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Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism

21 January 2018

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Dose-response effect of elevated plasma free fatty acid on insulin signaling

21 January 2018

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Dracorhodin perchlorate inhibits PI3K/Akt and NF-κB activation, up-regulates the expression of p53, and enhances apoptosis.

21 January 2018

1 reference

Salidroside improves behavioral and histological outcomes and reduces apoptosis via PI3K/Akt signaling after experimental traumatic brain injury

21 January 2018

1 reference

Inhibition of doxorubicin-induced HER3-PI3K-AKT signalling enhances apoptosis of ovarian cancer cells.

21 January 2018

1 reference

AKT/GSK3β-dependent autophagy contributes to the neuroprotection of limb remote ischemic postconditioning in the transient cerebral ischemic rat model.

21 January 2018

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Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

21 January 2018

1 reference

Glutathione protects cells against arsenite-induced toxicity

21 January 2018

1 reference

Nitric oxide and oxidative stress in vascular disease

21 January 2018

1 reference

Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells

21 January 2018

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Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

21 January 2018

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Nitric oxide and endothelial cellular senescence

21 January 2018

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Insulin-mediated stimulation of protein kinase Akt: A potent survival signaling cascade for endothelial cells

21 January 2018

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12 December 2020

Glutathione metabolism and its implications for health

1 reference

12 December 2020

Induction of adaptive response and enhancement of PC12 cell tolerance by 7-hydroxycholesterol and 15-deoxy-delta(12,14)-prostaglandin J2 through up-regulation of cellular glutathione via different mechanisms

1 reference

12 December 2020

Direct apoptotic effects of free fatty acids on human endothelial cells

1 reference

12 December 2020

Arsenite causes down-regulation of Akt and c-Fos, cell cycle dysfunction and apoptosis in glutathione-deficient cells

1 reference

12 December 2020

Increased oxidative stress is responsible for severer cerebral infarction in stroke-prone spontaneously hypertensive rats.

1 reference

12 December 2020

Dehydroepiandrosterone inhibits the activation and dysfunction of endothelial cells induced by high glucose concentration

1 reference

12 December 2020

Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage

1 reference

12 December 2020

Inducible nitric oxide synthase gene expression in brain following cerebral ischemia

1 reference

12 December 2020

[Programmed death of cells (apoptosis)]

1 reference

12 December 2020

Shear stress inhibits H2O2-induced apoptosis of human endothelial cells by modulation of the glutathione redox cycle and nitric oxide synthase

1 reference

12 December 2020

Glutathione: an overview of biosynthesis and modulation

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12 December 2020

Apoptosis of endothelial cells. Contribution to the pathophysiology of atherosclerosis?

1 reference

12 December 2020

Identifiers

DOI

10.1111/CNS.12068

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493493&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6493493&resulttype=core&format=json

14 May 2020

1 reference