Reactivation of p53 in cells expressing hepatitis B virus X-protein involves p53 phosphorylation and a reduction of Hdm2. (Q45396964)

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3 January 2020

title

Reactivation of p53 in cells expressing hepatitis B virus X-protein involves p53 phosphorylation and a reduction of Hdm2 (English)

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3 January 2020

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3 January 2020

Hyeseong Cho

9

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3 January 2020

author name string

Jin-Hee Wang

1

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3 January 2020

Sujeong Kim

3

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3 January 2020

Sunyoung Chae

4

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3 January 2020

Young Ik Lee

5

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3 January 2020

Wook-Hwan Kim

6

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3 January 2020

Jae-Ho Lee

7

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3 January 2020

Wankee Kim

8

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publication date

24 February 2008

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3 January 2020

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3 January 2020

volume

99

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3 January 2020

issue

5

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3 January 2020

page(s)

888-893

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Mdm2 promotes the rapid degradation of p53

3 January 2020

cites work

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00754.X

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

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Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species

21 January 2018

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The cellular response to p53: the decision between life and death

21 January 2018

1 reference

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Involvement of a cellular ubiquitin-protein ligase E6AP in the ubiquitin-mediated degradation of extensive substrates of high-risk human papillomavirus E6.

21 January 2018

1 reference

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Reactivation of mutant p53: molecular mechanisms and therapeutic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00754.X

Regulation of p53 function and stability by phosphorylation

21 January 2018

1 reference

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Chemotherapeutic drug, adriamycin, restores the function of p53 protein in hepatitis B virus X (HBx) protein-expressing liver cells

21 January 2018

1 reference

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Reactive oxygen species modulates the intracellular level of HBx viral oncoprotein

21 January 2018

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Human hepatitis B virus-X protein alters mitochondrial function and physiology in human liver cells

21 January 2018

1 reference

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Nucleotide sequence of integrated hepatitis B virus DNA and human flanking regions in the genome of the PLC/PRF/5 cell line

21 January 2018

1 reference

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The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.

21 January 2018

1 reference

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Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UV.

21 January 2018

1 reference

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Regulation of the accumulation and function of p53 by phosphorylation of two residues within the domain that binds to Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00754.X

Expression of hepatitis B virus X (HBx) gene is up-regulated by adriamycin at the post-transcriptional level

21 January 2018

1 reference

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The complexity of p53 stabilization and activation

21 January 2018

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The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage

21 January 2018

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Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

21 January 2018

1 reference

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Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00754.X

Cooperative phosphorylation at multiple sites is required to activate p53 in response to UV radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00754.X

Synergistic activation of p53 by inhibition of MDM2 expression and DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00754.X

Activation of p53 by roscovitine-mediated suppression of MDM2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2008.00754.X

10.1111/J.1349-7006.2008.00754.X

21 January 2018

Identifiers

DOI

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release_bekmbmqdhfbopavfvmqd42y5ky

3 January 2020

Fatcat ID

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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