Measuring phosphorylated Akt and other phosphoinositide 3-kinase-regulated phosphoproteins in primary lymphocytes. (Q46015581)

18 December 2017

title

Measuring phosphorylated Akt and other phosphoinositide 3-kinase-regulated phosphoproteins in primary lymphocytes. (English)

1 reference

18 December 2017

0 references

Amber C Donahue

1

1 reference

18 December 2017

Michael G Kharas

series ordinal

2

1 reference

18 December 2017

David A Fruman

series ordinal

3

1 reference

18 December 2017

language of work or name

English

0 references

publication date

1 January 2007

1 reference

18 December 2017

published in

Methods in Enzymology

1 reference

18 December 2017

volume

434

1 reference

18 December 2017

page(s)

131-154

1 reference

18 December 2017

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Phosphatidylinositol 3-kinase and NF-kappa B/Rel are at the divergence of CD40-mediated proliferation and survival pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

The dynamics of protein kinase B regulation during B cell antigen receptor engagement

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Unique signaling properties of B cell antigen receptor in mature and immature B cells: implications for tolerance and activation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110delta function in B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

A monoclonal antibody to visualize PtdIns(3,4,5)P(3) in cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Phosphoinositide 3-kinase: diverse roles in immune cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Proliferation and survival of activated B cells requires sustained antigen receptor engagement and phosphoinositide 3-kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

PI3K signaling controls cell fate at many points in B lymphocyte development and activation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Advances in procedures for the detection and localization of inositol phospholipid signals in cells, tissues, and enzyme assays

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Detection of intracellular phosphorylated STAT-1 by flow cytometry

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Phosphoinositide 3-kinase and its targets in B-cell and T-cell signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

The role of class I phosphoinositide 3-kinase in T-cell function and autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Quantitative measurement of phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

B cell receptor (BCR) cross-talk: IL-4 creates an alternate pathway for BCR-induced ERK activation that is phosphatidylinositol 3-kinase independent

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Bam32 Links the B Cell Receptor to ERK and JNK and Mediates B Cell Proliferation but Not Survival

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Imaging antigen-induced PI3K activation in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Frontline: The p85alpha isoform of phosphoinositide 3-kinase is essential for a subset of B cell receptor-initiated signaling responses.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Convergence of signaling pathways on the activation of ERK in B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Activation of phosphoinositide 3-kinase and Src family kinase is required for respiratory burst in rat neutrophils stimulated with artocarpol A

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Antigen receptor proximal signaling in splenic B-2 cell subsets

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Coligation of the B cell receptor with complement receptor type 2 (CR2/CD21) using its natural ligand C3dg: activation without engagement of an inhibitory signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Immunocytochemical detection of phosphatidylinositol 3-kinase activation by insulin and leptin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

PI3K-signalling in B- and T-cells: insights from gene-targeted mice

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Roles for phosphoinositide 3-kinases, Bruton's tyrosine kinase, and Jun kinases in B lymphocyte chemotaxis and homing.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Activation of the PKB/AKT pathway by ICAM-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

PI3-kinase and TOR: PIKTORing cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Causal protein-signaling networks derived from multiparameter single-cell data

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Synthesis and function of 3-phosphorylated inositol lipids

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Bacterial lipopolysaccharide induced B cell activation is mediated via a phosphatidylinositol 3-kinase dependent signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Vav-Dependent and Vav-Independent Phosphatidylinositol 3-Kinase Activation in Murine B Cells Determined by the Nature of the Stimulus

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

RIP links TLR4 to Akt and is essential for cell survival in response to LPS stimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

TOR signaling in growth and metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2934008-1

7 January 2021

10.1016/S0076-6879(07)34008-1

Identifiers

DOI

1 reference

18 December 2017

1 reference

18 December 2017