Cannabinoid receptor 1 mediates glucocorticoid-induced bone loss in rats by perturbing bone mineral acquisition and marrow adipogenesis (Q46292223)

21 December 2017

title

Cannabinoid receptor 1 mediates glucocorticoid-induced bone loss in rats by perturbing bone mineral acquisition and marrow adipogenesis (English)

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21 December 2017

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Jih-Yang Ko

1

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Re-Wen Wu

2

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Shu-Jui Kuo

3

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Ming-Wen Chen

4

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Da-Wei Yeh

5

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Huei-Ching Ke

6

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Shin-Long Wu

7

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Feng-Sheng Wang

8

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publication date

29 November 2011

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21 December 2017

published in

Arthritis & Rheumatology

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volume

64

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issue

4

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page(s)

1204-1214

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Teriparatide or alendronate in glucocorticoid-induced osteoporosis

cites work

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Glucocorticoid-induced bone loss in mice can be reversed by the actions of parathyroid hormone and risedronate on different pathways for bone formation and mineralization

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Selective regulation of bone cell apoptosis by translational isoforms of the glucocorticoid receptor

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Intermittent parathyroid hormone administration counteracts the adverse effects of glucocorticoids on osteoblast and osteocyte viability, bone formation, and strength in mice

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Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: a longitudinal study of gene expression in bone tissue from glucocorticoid-treated mice

21 January 2018

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Glucocorticoids suppress bone formation via the osteoclast

21 January 2018

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Prevention of glucocorticoid-induced bone loss in mice by inhibition of RANKL.

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Femoral head histology subsequent to ischemia, reperfusion and steroid treatment

21 January 2018

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Leptin regulation of bone resorption by the sympathetic nervous system and CART

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Critical interplay between neuropeptide Y and sex steroid pathways in bone and adipose tissue homeostasis

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Novel role of Y1 receptors in the coordinated regulation of bone and energy homeostasis

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Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition

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Endocrine regulation of energy metabolism by the skeleton

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Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: the role of eNOS, p38 MAPK, and AMPK pathways.

21 January 2018

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Leptin controls adipose tissue lipogenesis via central, STAT3-independent mechanisms

21 January 2018

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Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia

21 January 2018

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Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors

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Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees

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Peripheral cannabinoid receptor, CB2, regulates bone mass

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Opposing crosstalk between leptin and glucocorticoids rapidly modulates synaptic excitation via endocannabinoid release.

21 January 2018

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Inhibition of glycogen synthase kinase-3beta attenuates glucocorticoid-induced bone loss

21 January 2018

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Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

21 January 2018

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The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

21 January 2018

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The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption.

21 January 2018

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A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss

21 January 2018

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Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory

21 January 2018

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The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling.

21 January 2018

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Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling.

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Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle

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CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3beta/beta-catenin signaling

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Fibroblast growth factor receptor 2 promotes osteogenic differentiation in mesenchymal cells via ERK1/2 and protein kinase C signaling

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Glucocorticoids, osteocytes, and skeletal fragility: the role of bone vascularity

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Human osteoblasts derived from mesenchymal stem cells express adipogenic markers upon coculture with bone marrow adipocytes.

21 January 2018

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Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity

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CB1 antagonism exerts specific molecular effects on visceral and subcutaneous fat and reverses liver steatosis in diet-induced obese mice

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In vitro and in vivo effects of adiponectin on bone

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Adiponectin stimulates osteoblast differentiation through induction of COX2 in mesenchymal progenitor cells

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Leptin treatment induces loss of bone marrow adipocytes and increases bone formation in leptin-deficient ob/ob mice.

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Relationship between adipocyte size and adipokine expression and secretion

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CB2 cannabinoid receptor targets mitogenic Gi protein-cyclin D1 axis in osteoblasts

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21 January 2018

Identifiers

DOI

10.1002/ART.33457

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21 December 2017

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21 December 2017