A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells. (Q46402239)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Mattias Belting

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Srikumar M Raja

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Sunil S Metkar

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Stefan Höning

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Baikun Wang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

William A Russin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Nina H Pipalia

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Cheikh Menaa

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Xuefang Cao

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Christopher J Froelich

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

0 references

publication date

23 March 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

9 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

280

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

20752-20761

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

The immunological synapse of CTL contains a secretory domain and membrane bridges.

9 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

The secretory synapse: the secrets of a serial killer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Nuclear war: the granzyme A-bomb

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Granzyme B-mediated apoptosis--the elephant and the blind men?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

The granzyme B-serglycin complex from cytotoxic granules requires dynamin for endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Unimpaired allorejection of cells deficient for the mannose 6-phosphate receptors Mpr300 and Mpr46.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Animal cell mutants defective in glycosaminoglycan biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

A single mutation affects both N-acetylglucosaminyltransferase and glucuronosyltransferase activities in a Chinese hamster ovary cell mutant defective in heparan sulfate biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Protein-heparin interactions measured by BIAcore 2000 are affected by the method of heparin immobilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Endocytosed Cation-Independent Mannose 6-Phosphate Receptor Traffics via the Endocytic Recycling Compartment en Route to thetrans-Golgi Network and a Subpopulation of Late Endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Avidin is a heparin-binding protein. Affinity, specificity and structural analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Developmental changes in heparan sulfate expression: in situ detection with mAbs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

An animal cell mutant defective in heparan sulfate hexuronic acid 2-O-sulfation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Structural differences and the presence of unsubstituted amino groups in heparan sulphates from different tissues and species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Structural characterization of human liver heparan sulfate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Protein transduction domains and their utility in gene therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Ligation of cell surface heparan sulfate proteoglycans by antibody-coated beads stimulates phagocytic uptake into epithelial cells: a model for cellular invasion by Neisseria gonorrhoeae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Membrane receptors are not required to deliver granzyme B during killer cell attack

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Endocytosing the death sentence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

Detection of functional cell surface perforin by flow cytometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501181200

21 January 2018

Identifiers

DOI

10.1074/JBC.M501181200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15788411%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference