Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons (Q46407035)

21 December 2017

http://europepmc.org/abstract/MED/18753379

title

Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons (English)

1 reference

21 December 2017

http://europepmc.org/abstract/MED/18753379

author name string

Koichi Hasegawa

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670824&resulttype=core&format=json

16 May 2020

Kazuaki Yoshikawa

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670824&resulttype=core&format=json

16 May 2020

language of work or name

English

0 references

publication date

1 August 2008

1 reference

21 December 2017

http://europepmc.org/abstract/MED/18753379

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670824&resulttype=core&format=json

16 May 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670824&resulttype=core&format=json

16 May 2020

issue

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670824&resulttype=core&format=json

16 May 2020

page(s)

8772-8784

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670824&resulttype=core&format=json

Physical and functional interactions of neuronal growth suppressor necdin with p53

16 May 2020

cites work

1 reference

12 December 2020

Activation of neuronal caspase-3 by intracellular accumulation of wild-type Alzheimer amyloid precursor protein.

1 reference

12 December 2020

Gene expression profile of aging and its retardation by caloric restriction

1 reference

12 December 2020

Disruption of the mouse necdin gene results in early post-natal lethality

1 reference

12 December 2020

FHL2, a novel tissue-specific coactivator of the androgen receptor

1 reference

12 December 2020

Cellular and subcellular localization of necdin in fetal and adult mouse brain

1 reference

12 December 2020

NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis

1 reference

12 December 2020

Disruption of the mouse Necdin gene results in hypothalamic and behavioral alterations reminiscent of the human Prader-Willi syndrome.

1 reference

12 December 2020

p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

1 reference

12 December 2020

Necdin acts as a transcriptional repressor that interacts with multiple guanosine clusters

1 reference

12 December 2020

Negative control of p53 by Sir2alpha promotes cell survival under stress

1 reference

12 December 2020

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

1 reference

12 December 2020

The MAGE proteins: emerging roles in cell cycle progression, apoptosis, and neurogenetic disease

1 reference

12 December 2020

Necdin is required for terminal differentiation and survival of primary dorsal root ganglion neurons

1 reference

12 December 2020

Ectopic expression of necdin induces differentiation of mouse neuroblastoma cells

1 reference

12 December 2020

The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis

1 reference

12 December 2020

Absence of Ndn, encoding the Prader-Willi syndrome-deleted gene necdin, results in congenital deficiency of central respiratory drive in neonatal mice

1 reference

12 December 2020

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

1 reference

12 December 2020

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

1 reference

12 December 2020

Expression of necdin, an embryonal carcinoma-derived nuclear protein, in developing mouse brain

1 reference

12 December 2020

1 reference

12 December 2020

Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain.

1 reference

12 December 2020

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

1 reference

12 December 2020

Necdin interacts with the Msx2 homeodomain protein via MAGE-D1 to promote myogenic differentiation of C2C12 cells

1 reference

12 December 2020

MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription

1 reference

12 December 2020

Deacetylation of p53 after nerve growth factor treatment in PC12 cells as a post-translational modification mechanism of neurotrophin-induced tumor suppressor activation

1 reference

12 December 2020

Functional domains of necdin for protein-protein interaction, nuclear matrix targeting, and cell growth suppression

1 reference

12 December 2020

Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth

1 reference

12 December 2020

Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation

1 reference

12 December 2020

p53 in neuronal apoptosis

1 reference

12 December 2020

Developmental abnormalities of neuronal structure and function in prenatal mice lacking the prader-willi syndrome gene necdin

1 reference

12 December 2020

Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival

1 reference

12 December 2020

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

1 reference

12 December 2020

Neuroprotection by histone deacetylase-related protein

1 reference

12 December 2020

Necdin promotes GABAergic neuron differentiation in cooperation with Dlx homeodomain proteins.

1 reference

12 December 2020

Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate.

1 reference

12 December 2020

MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents

1 reference

12 December 2020

Brain developmental abnormalities in Prader-Willi syndrome detected by diffusion tensor imaging

1 reference

12 December 2020

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

1 reference

12 December 2020

The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration

1 reference

12 December 2020

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

1 reference

12 December 2020

Intracranial abnormalities detected by three-dimensional magnetic resonance imaging in Prader-Willi syndrome

1 reference

12 December 2020

Necdin downregulates CDC2 expression to attenuate neuronal apoptosis.

1 reference

12 December 2020

Sensory defects in Necdin deficient mice result from a loss of sensory neurons correlated within an increase of developmental programmed cell death

1 reference

12 December 2020

Single mage gene in the chicken genome encodes CMage, a protein with functional similarities to mammalian type II Mage proteins.

1 reference

12 December 2020

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

1 reference

12 December 2020

Microarray analysis of the cellular pathways involved in the adaptation to and progression of motor neuron injury in the SOD1 G93A mouse model of familial ALS.

1 reference

12 December 2020

Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity

1 reference

12 December 2020

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

1 reference

12 December 2020

DBC1 is a negative regulator of SIRT1

1 reference

12 December 2020

Negative regulation of the deacetylase SIRT1 by DBC1

1 reference

12 December 2020

Drosophila MAGE controls neural precursor proliferation in postembryonic neurogenesis

1 reference

12 December 2020

Loss of the Prader-Willi syndrome protein necdin causes defective migration, axonal outgrowth, and survival of embryonic sympathetic neurons.

1 reference

12 December 2020

A novel brain-specific mRNA encoding nuclear protein (necdin) expressed in neurally differentiated embryonal carcinoma cells

1 reference

12 December 2020

Structure and expression of the mouse necdin gene. Identification of a postmitotic neuron-restrictive core promoter

1 reference

12 December 2020

Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity

1 reference

12 December 2020

Evidence for p53-mediated modulation of neuronal viability.

1 reference

12 December 2020

Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons

1 reference

12 December 2020

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

1 reference

12 December 2020

The necdin gene is deleted in Prader-Willi syndrome and is imprinted in human and mouse

1 reference

12 December 2020

The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal region

1 reference

12 December 2020

Necdin, a postmitotic neuron-specific growth suppressor, interacts with viral transforming proteins and cellular transcription factor E2F1

1 reference

12 December 2020

The human chromosomal gene for necdin, a neuronal growth suppressor, in the Prader-Willi syndrome deletion region

1 reference

12 December 2020

Phosphorylation of p53 serine 15 increases interaction with CBP

1 reference

12 December 2020

10.1523/JNEUROSCI.3052-08.2008

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670824&resulttype=core&format=json

16 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670824&resulttype=core&format=json

16 May 2020

1 reference