Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice. (Q46595342)

http://europepmc.org/abstract/MED/15140940

23 December 2017

title

Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729387&resulttype=core&format=json

12 May 2020

5

Eliezer Masliah

2 references

23 December 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729387&resulttype=core&format=json

12 May 2020

6

Lennart Mucke

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729387&resulttype=core&format=json

12 May 2020

author name string

Jeannie Chin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729387&resulttype=core&format=json

12 May 2020

Jorge J Palop

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729387&resulttype=core&format=json

12 May 2020

Gui-Qiu Yu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729387&resulttype=core&format=json

12 May 2020

Nobuhiko Kojima

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729387&resulttype=core&format=json

12 May 2020

language of work or name

English

0 references

publication date

1 May 2004

1 reference

http://europepmc.org/abstract/MED/15140940

23 December 2017

published in

Journal of Neuroscience

1 reference

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12 May 2020

volume

24

1 reference

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12 May 2020

page(s)

4692-4697

1 reference

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12 May 2020

issue

19

1 reference

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Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

12 May 2020

cites work

1 reference

12 December 2020

Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration.

1 reference

12 December 2020

Higher seizure susceptibility and enhanced tyrosine phosphorylation of N-methyl-D-aspartate receptor subunit 2B in fyn transgenic mice

1 reference

12 December 2020

Cerebral amyloid induces aberrant axonal sprouting and ectopic terminal formation in amyloid precursor protein transgenic mice.

1 reference

12 December 2020

Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits.

1 reference

12 December 2020

Apolipoprotein E and cognitive performance

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12 December 2020

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

12 December 2020

Acetylcholinesterase-positive fiber deafferentation and cell shrinkage in the septohippocampal pathway of aged amyloid precursor protein london mutant transgenic mice

1 reference

12 December 2020

Disturbance of neuronal plasticity is a critical pathogenetic event in Alzheimer's disease

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12 December 2020

Integrins mediate functional pre- and postsynaptic maturation at a hippocampal synapse

1 reference

12 December 2020

Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease

1 reference

12 December 2020

Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway

1 reference

12 December 2020

Alzheimer's disease and Abeta toxicity: from top to bottom

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12 December 2020

Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases.

1 reference

12 December 2020

The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

1 reference

12 December 2020

NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1

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12 December 2020

Uptake and pathogenic effects of amyloid beta peptide 1-42 are enhanced by integrin antagonists and blocked by NMDA receptor antagonists

1 reference

12 December 2020

Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

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12 December 2020

Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.

1 reference

12 December 2020

Aberrant activation of focal adhesion proteins mediates fibrillar amyloid beta-induced neuronal dystrophy.

1 reference

12 December 2020

APP processing and synaptic function

1 reference

12 December 2020

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

1 reference

12 December 2020

Scaffolding of Fyn kinase to the NMDA receptor determines brain region sensitivity to ethanol

1 reference

12 December 2020

Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits

1 reference

12 December 2020

Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

1 reference

12 December 2020

Three-dimensional analysis of the relationship between synaptic pathology and neuropil threads in Alzheimer disease.

1 reference

12 December 2020

Patterns of aberrant sprouting in Alzheimer's disease

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12 December 2020

The expression of GAP-43 in relation to neuronal growth and plasticity: when, where, how, and why?

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12 December 2020

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity.

1 reference

12 December 2020

Plasticity of hippocampal circuitry in Alzheimer's disease.

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12 December 2020

Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease.

1 reference

12 December 2020

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12 December 2020

Interaction of beta-amyloid peptides with integrins in a human nerve cell line

1 reference

12 December 2020

Synaptotrophic effects of human amyloid β protein precursors in the cortex of transgenic mice

1 reference

12 December 2020

The protein tyrosine kinase, fyn, in Alzheimer's disease pathology.

1 reference

12 December 2020

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

1 reference

12 December 2020

Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene

1 reference

12 December 2020

Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice.

1 reference

12 December 2020

Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

1 reference

12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

12 December 2020

Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex

1 reference

12 December 2020

Reg1ulatory role and molecular interactions of a cell-surface heparan sulfate proteoglycan (N-syndecan) in hippocampal long-term potentiation.

1 reference

12 December 2020

10.1523/JNEUROSCI.0277-04.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729387&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6729387&resulttype=core&format=json

12 May 2020

1 reference