TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy. (Q46929681)

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8 March 2020

title

TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy (English)

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8 March 2020

4

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8 March 2020

Ismail Syed

5

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8 March 2020

Julia Santos

6

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8 March 2020

author name string

Renu A Kowluru

1

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8 March 2020

Anjaneyulu Kowluru

2

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8 March 2020

Rajakrishnan Veluthakal

3

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8 March 2020

Manish Mishra

7

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8 March 2020

publication date

20 February 2014

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8 March 2020

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8 March 2020

volume

57

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8 March 2020

page(s)

1047-1056

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8 March 2020

issue

5

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https://scigraph.springernature.com/pub.10.1007/s00125-014-3194-z

8 March 2020

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cites work

Diabetic retinopathy: mitochondrial dysfunction and retinal capillary cell death

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Diabetes-induced mitochondrial dysfunction in the retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Mitochondria damage in the pathogenesis of diabetic retinopathy and in the metabolic memory associated with its continued progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

The pathobiology of diabetic complications: a unifying mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

The neutrophil NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

NADPH oxidases: not just for leukocytes anymore!

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Regulation of the phagocyte NADPH oxidase by Rac GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Dual role of Rac in the assembly of NADPH oxidase, tethering to the membrane and activation of p67phox: a study based on mutagenesis of p67phox-Rac1 chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Regulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Small G proteins in islet beta-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

The many faces of the guanine-nucleotide exchange factor trio.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Upregulation of phagocyte-like NADPH oxidase by cytokines in pancreatic beta-cells: attenuation of oxidative and nitrosative stress by 2-bromopalmitate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Mitochondrial DNA damage and its potential role in retinal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

High glucose disrupts mitochondrial morphology in retinal endothelial cells: implications for diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Mitochondrial biogenesis and the development of diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

A compensatory mechanism protects retinal mitochondria from initial insult in diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Epigenetic changes in mitochondrial superoxide dismutase in the retina and the development of diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Abrogation of MMP-9 gene protects against the development of retinopathy in diabetic mice by preventing mitochondrial damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Diabetic retinopathy and signaling mechanism for activation of matrix metalloproteinase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Mitochondria DNA replication and DNA methylation in the metabolic memory associated with continued progression of diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Damaged mitochondrial DNA replication system and the development of diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries: regulation by angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Rho guanosine diphosphate-dissociation inhibitor plays a negative modulatory role in glucose-stimulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Dominant-negative alpha-subunit of farnesyl- and geranyltransferase inhibits glucose-stimulated, but not KCl-stimulated, insulin secretion in INS 832/13 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Role of mitochondria biogenesis in the metabolic memory associated with the continued progression of diabetic retinopathy and its regulation by lipoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

NADPH oxidases: functions and pathologies in the vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

The Nox family of NADPH oxidases: friend or foe of the vascular system?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Friendly, and not so friendly, roles of Rac1 in islet β-cell function: lessons learnt from pharmacological and molecular biological approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Palmitate-induced apoptosis in cultured bovine retinal pericytes: roles of NAD(P)H oxidase, oxidant stress, and ceramide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Role of NADPH oxidase in retinal vascular inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Photoreceptor cells are major contributors to diabetes-induced oxidative stress and local inflammation in the retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Role of NADPH oxidase and Stat3 in statin-mediated protection against diabetic retinopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Suppression of retinal peroxisome proliferator-activated receptor gamma in experimental diabetes and oxygen-induced retinopathy: role of NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Reactive oxygen species, Nox and angiotensin II in angiogenesis: implications for retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and lipid peroxides and the loss of mitochondrial membrane potential in pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Rac1 is required for cardiomyocyte apoptosis during hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Neural crest cell-specific deletion of Rac1 results in defective cell-matrix interactions and severe craniofacial and cardiovascular malformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3194-Z

Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1.

21 January 2018

1 reference

12 December 2020

Oxidative damage in the retinal mitochondria of diabetic mice: possible protection by superoxide dismutase

1 reference

12 December 2020

Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation

1 reference

12 December 2020

Inhibition of NAD(P)H oxidase reduces apoptosis and avascular retina in an animal model of retinopathy of prematurity

1 reference

12 December 2020

1 reference

12 December 2020