Scientific Opinion on the Tolerable Upper Intake Level of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA) (Q47152105)

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scientific article published in July 2012

Language	Label	Description	Also known as
English	Scientific Opinion on the Tolerable Upper Intake Level of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA)	scientific article published in July 2012

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scholarly article

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Scientific Opinion on the Tolerable Upper Intake Level of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA) (English)

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EFSA Panel On Dietetic Products, Nutrition And Allergies

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Efsa Panel On Dietetic Products, Nutrition And Allergies (nda)

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publication date

July 2012

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10

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7

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Dietary intakes and food sources of n-6 and n-3 PUFA in French adult men and women

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Double-blind, randomized, controlled trial of fish oil supplements in prevention of recurrence of stenosis after coronary angioplasty

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Effects of omega-3 fatty acids on serum markers of cardiovascular disease risk: a systematic review

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Fish oil supplementation in pregnancy lowers F2-isoprostanes in neonates at high risk of atopy

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Dietary intake and sources of long-chain n-3 PUFAs in German adults

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Fish and seafood consumption and omega 3 intake in French coastal populations: CALIPSO survey.

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Effect of eicosapentaenoic and docosahexaenoic acid on resting and exercise-induced inflammatory and oxidative stress biomarkers: a randomized, placebo controlled, cross-over study

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Fish oils and low-molecular-weight heparin for the reduction of restenosis after percutaneous transluminal coronary angioplasty. The EMPAR Study

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N-3 Fatty acids for the prevention of atrial fibrillation after coronary artery bypass surgery: a randomized, controlled trial.

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n-3 fatty acids in the treatment of diabetic patients: biological rationale and clinical data

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Scientific Opinion on Dietary Reference Values for fats, including saturated fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol

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Guidance on the scientific requirements for health claims related to antioxidants, oxidative damage and cardiovascular health

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Safety of the omega-3 fatty acid, eicosapentaenoic acid (EPA) in psychiatric patients: results from a randomized, placebo-controlled trial

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Fish oil in people with type 2 diabetes mellitus

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Omega-3 fatty acids in high-risk cardiovascular patients: a meta-analysis of randomized controlled trials

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Fish oil and glycemic control in diabetes. A meta-analysis

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Review of the effects of omega-3 supplementation in dialysis patients

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Effect of the dietary fat quality on insulin sensitivity

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Fish oil, insulin sensitivity, insulin secretion and glucose tolerance in healthy people: is there any effect of fish oil supplementation in relation to the type of background diet and habitual dietary intake of n-6 and n-3 fatty acids?

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Expert opinion: omega-3 fatty acids and bleeding-cause for concern?

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Omega-3 polyunsaturated fatty acids (PUFA) for type 2 diabetes mellitus

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Potential impact of omega-3 treatment on cardiovascular disease in type 2 diabetes

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Fish consumption and risk of stroke in men

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(n-3) Fatty Acids: Clinical Trials in People with Type 2 Diabetes

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Gamma-tocopherol and docosahexaenoic acid decrease inflammation in dialysis patients.

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Omega 3 fatty acids for prevention and treatment of cardiovascular disease

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Effects of eicosapentaenoic acid and docosahexaenoic acid on low-density lipoprotein cholesterol and other lipids: a review

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Dietary intake of total marine n-3 polyunsaturated fatty acids, eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid and the risk of acute coronary syndrome - a cohort study

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Intake of very-long-chain n-3 fatty acids related to social status and lifestyle.

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Docosapentaenoic acid (22:5n-3): a review of its biological effects.

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A method for assessing dietary intakes of n-3 long-chain polyunsaturated fatty acids and trans fatty acids in an Irish adult population

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Herring ( Clupea harengus) intake influences lipoproteins but not inflammatory and oxidation markers in overweight men.

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The omega-3 fatty acids EPA and DHA decrease plasma F(2)-isoprostanes: Results from two placebo-controlled interventions.

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Fish oil supplementation in type 2 diabetes: a quantitative systematic review

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Effect of eicosapentaenoic acid and docosahexaenoic acid on oxidative stress and inflammatory markers in treated-hypertensive type 2 diabetic subjects.

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Quantification of isoprostanes as indices of oxidant stress and the risk of atherosclerosis in humans

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The effect of dietary docosahexaenoic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans

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Randomised controlled trial of effect of fish-oil supplementation on pregnancy duration

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Isoprostanes and other markers of peroxidation in atherosclerosis

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OMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction

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Effects of serum lipid levels on restenosis after coronary angioplasty

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Age and time trends in fish consumption pattern of children and adolescents, and consequences for the intake of long-chain n-3 polyunsaturated fatty acids.

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n-6 and n-3 PUFA intakes of pre-school children in Flanders, Belgium.

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Importance of seafood as nutrient source in the diet of Belgian adolescents

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The influence of n-3 PUFA supplements and n-3 PUFA enriched foods on the n-3 LC PUFA intake of Flemish women

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Dietary intakes and food sources of fatty acids for Belgian women, focused on n-6 and n-3 polyunsaturated fatty acids.

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Consumption of fish and fish oils and decreased risk of stroke

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Effects of an open-label pilot study with high-dose EPA/DHA concentrates on plasma phospholipids and behavior in children with attention deficit hyperactivity disorder

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Effect of preterm formula with and without long-chain polyunsaturated fatty acids on the urinary excretion of F2-isoprostanes and 8-epi-prostaglandin F2alpha

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Fish consumption and polyunsaturated fatty acids in relation to psychological distress

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Reduction in the recurrence of stroke by eicosapentaenoic acid for hypercholesterolemic patients: subanalysis of the JELIS trial

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Nutrition, supplements, and vitamins in platelet function and bleeding

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Effects of eicosapentaenoic acid versus docosahexaenoic acid on serum lipids: a systematic review and meta-analysis.

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Dietary intake and status of n-3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters, vegetarians, and vegans and the product-precursor ratio [corrected] of α-linolenic acid to long-chain n-3 polyunsaturated fa

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Effects of purified eicosapentaenoic acid and docosahexaenoic acid on platelet, fibrinolytic and vascular function in hypertensive type 2 diabetic patients.

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Effects of docosahexaenoic acid supplementation on blood lipids, estrogen metabolism, and in vivo oxidative stress in postmenopausal vegetarian women

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Effects of n-3 PUFA supplementation on plasma soluble adhesion molecules: a meta-analysis of randomized controlled trials

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Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis

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Insights into the inhibition of platelet activation by omega-3 polyunsaturated fatty acids: Beyond aspirin and clopidogrel

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Do fish oils prevent restenosis after coronary angioplasty?

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10.2903/J.EFSA.2012.2815

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