Positive selection has driven the evolution of the Drosophila insulin-like receptor (InR) at different timescales (Q47930345)

6 February 2018

title

Positive selection has driven the evolution of the Drosophila insulin-like receptor (InR) at different timescales (English)

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6 February 2018

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6 February 2018

Montserrat Aguadé i Porres

series ordinal

2

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6 February 2018

publication date

27 April 2009

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6 February 2018

Molecular Biology and Evolution

published in

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6 February 2018

volume

26

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6 February 2018

issue

8

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6 February 2018

page(s)

1723-1732

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6 February 2018

Contrasting patterns of X-linked and autosomal nucleotide variation in Drosophila melanogaster and Drosophila simulans.

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Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation

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Analysis of conserved noncoding DNA in Drosophila reveals similar constraints in intergenic and intronic sequences.

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Linkage limits the power of natural selection in Drosophila

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Genetic links between diet and lifespan: shared mechanisms from yeast to humans

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Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

21 January 2018

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QTL mapping reveals a striking coincidence in the positions of genomic regions associated with adaptive variation in body size in parallel clines of Drosophila melanogaster on different continents

21 January 2018

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Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis

21 January 2018

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Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

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Evolution of genes and genomes on the Drosophila phylogeny

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Genetic variation of Drosophila melanogaster natural populations

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Insulin and its receptor: structure, function and evolution

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Structural biology of insulin and IGF1 receptors: implications for drug design

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Structure and ligand specificity of the Drosophila melanogaster insulin receptor

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Genetic analysis of insulin signaling in Drosophila

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Role of insulin-like signalling in Drosophila lifespan

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The functions of insulin signaling: size isn't everything, even in Drosophila

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Quantitative genetic analysis of natural variation in body size in Drosophila melanogaster

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Patterns of evolutionary constraints in intronic and intergenic DNA of Drosophila.

21 January 2018

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Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila

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Control of growth and organ size in Drosophila

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Patterns of diversity and linkage disequilibrium within the cosmopolitan inversion In(3R)Payne in Drosophila melanogaster are indicative of coadaptation

21 January 2018

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The ligand specificities of the insulin receptor and the insulin-like growth factor I receptor reside in different regions of a common binding site

21 January 2018

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A novel Drosophila insulin receptor: fly in the ointment or evolutionary conservation?

21 January 2018

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Adaptive protein evolution at the Adh locus in Drosophila

21 January 2018

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Structure of the insulin receptor ectodomain reveals a folded-over conformation

21 January 2018

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Intraspecific nuclear DNA variation in Drosophila

21 January 2018

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Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control

21 January 2018

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Delayed male maturity is a cost of producing large sperm in Drosophila

21 January 2018

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Widespread Discordance of Gene Trees with Species Tree in Drosophila: Evidence for Incomplete Lineage Sorting

21 January 2018

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MODELTEST: testing the model of DNA substitution

21 January 2018

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DnaSP, DNA polymorphism analyses by the coalescent and other methods

21 January 2018

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The Drosophila insulin receptor contains a novel carboxyl-terminal extension likely to play an important role in signal transduction

21 January 2018

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Insulin signalling and the regulation of glucose and lipid metabolism

21 January 2018

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Why size matters: altering cell size

21 January 2018

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Genetic control of cell size

21 January 2018

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On the Subdivision of the Genus Drosophila

21 January 2018

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False-positive selection identified by ML-based methods: examples from the Sig1 gene of the diatom Thalassiosira weissflogii and the tax gene of a human T-cell lymphotropic virus

21 January 2018

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The neuroendocrine regulation of Drosophila aging

21 January 2018

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

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Signaling and function of insulin-like peptides in insects

21 January 2018

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21 January 2018

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Likelihood ratio tests for detecting positive selection and application to primate lysozyme evolution

21 January 2018

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Synonymous and nonsynonymous rate variation in nuclear genes of mammals.

21 January 2018

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Codon-substitution models for detecting molecular adaptation at individual sites along specific lineages

21 January 2018

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Codon-substitution models to detect adaptive evolution that account for heterogeneous selective pressures among site classes

21 January 2018

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Bayes empirical bayes inference of amino acid sites under positive selection

21 January 2018

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The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP088

Evaluation of an improved branch-site likelihood method for detecting positive selection at the molecular level

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP088

I-TASSER server for protein 3D structure prediction

21 January 2018

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https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP088

TreeSAAP: Selection on Amino Acid Properties using phylogenetic trees

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSP088

21 January 2018

Identifiers

DOI

10.1093/MOLBEV/MSP088

1 reference

6 February 2018

release_76t5isxy2remdid2xn3cp7wg6u

Fatcat ID

0 references

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6 February 2018