Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis. (Q33946679)

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English	Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.	scientific article

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scholarly article

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11 November 2019

Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis (English)

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11 November 2019

apoptotic process

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based on heuristic

inferred from title

Prakash Nagarkatti

9

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11 November 2019

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11 November 2019

Jeffery D. Molkentin

11

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11 November 2019

author name string

L Qiao

1

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11 November 2019

E Studer

2

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K Leach

3

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11 November 2019

R McKinstry

4

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11 November 2019

S Gupta

5

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11 November 2019

R Decker

6

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11 November 2019

R Kukreja

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11 November 2019

K Valerie

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11 November 2019

R Schmidt-Ullrich

12

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11 November 2019

P B Fisher

13

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11 November 2019

S Grant

14

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11 November 2019

P B Hylemon

15

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11 November 2019

P Dent

16

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11 November 2019

publication date

1 September 2001

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11 November 2019

Molecular Biology of the Cell

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11 November 2019

12

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11 November 2019

2629-2645

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11 November 2019

9

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11 November 2019

The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits Fas apoptosis upstream of bid in rodent hepatocytes

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5 July 2018

Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition

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5 July 2018

Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis

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5 July 2018

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

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5 July 2018

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

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5 July 2018

MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly

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5 July 2018

Expression of Bcl-2 inhibited Fas-mediated apoptosis in human hepatocellular carcinoma BEL-7404 cells

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5 July 2018

A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes

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5 July 2018

Bid, a critical mediator for apoptosis induced by the activation of Fas/TNF-R1 death receptors in hepatocytes

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5 July 2018

Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas.

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The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade

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5 July 2018

Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway

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5 July 2018

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c-raf-1 depletion and tumor responses in patients treated with the c-raf-1 antisense oligodeoxynucleotide ISIS 5132 (CGP 69846A).

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Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway

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Expression of human papilloma virus E7 protein causes apoptosis and inhibits DNA synthesis in primary hepatocytes via increased expression of p21(Cip-1/WAF1/MDA6).

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Role of Fas-Fas ligand interactions in 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD)-induced immunotoxicity: increased resistance of thymocytes from Fas-deficient (lpr) and Fas ligand-defective (gld) mice to TCDD-induced toxicity

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

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Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

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Mitogen-activated protein kinase kinase antagonized fas-associated death domain protein-mediated apoptosis by induced FLICE-inhibitory protein expression

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Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production

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The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes

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Comparison of the effects of bile acids on cell viability and DNA synthesis by rat hepatocytes in primary culture

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Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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12 December 2020

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Farnesyltransferase inhibitors potentiate the antitumor effect of radiation on a human tumor xenograft expressing activated HRAS

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Characterization of bile salt-induced apoptosis in colon cancer cell lines

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12 December 2020

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Hepatocytes in the bile duct-ligated rat express Bcl-2

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12 December 2020

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Primary biliary cirrhosis

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12 December 2020

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Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

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12 December 2020

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Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver

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Extrahepatic biliary obstruction impairs microvascular perfusion and increases leukocyte adhesion in rat liver

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Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat

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Effect of high concentrations of bile acids on cultured hepatocytes

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12 December 2020

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based on heuristic

inferred from PubMed ID database lookup

Overexpression of Apaf-1 promotes apoptosis of untreated and paclitaxel- or etoposide-treated HL-60 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11553704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo: evidence for a postmitochondrial processing of caspase-8

1 reference

https://pubmed.ncbi.nlm.nih.gov/11553704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and Bax.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11553704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BID-dependent and BID-independent pathways for BAX insertion into mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/11553704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Head and neck cancer as a clinical model for molecular targeting of therapy: combining EGFR blockade with radiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11553704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11553704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholecystocolonic fistula: malabsorptive consequences of lost bile acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/11553704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity of bile acids on the electron transport chain of isolated rat liver mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/11553704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ursodeoxycholate (UDCA) inhibits the mitochondrial membrane permeability transition induced by glycochenodeoxycholate: a mechanism of UDCA cytoprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/11553704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear serine protease activity contributes to bile acid-induced apoptosis in hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11553704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein tyrosine phosphatases and the control of cellular signaling responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/11553704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bile salt-induced apoptosis of hepatocytes involves activation of protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/11553704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.12.9.2629

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11553704%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

release_qyrvcnyj2vhhtowcnnflyt55je

1 reference

https://api.fatcat.wiki/v0/release/qyrvcnyj2vhhtowcnnflyt55je

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11553704%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11553704%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

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