Transgenic mice expressing the PS1-A246E mutation: effects on spatial learning, exploration, anxiety, and motor coordination. (Q48421950)

11 February 2018

title

Transgenic mice expressing the PS1-A246E mutation: effects on spatial learning, exploration, anxiety, and motor coordination. (English)

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11 February 2018

author name string

Lalonde R

series ordinal

1

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11 February 2018

Qian S

series ordinal

2

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11 February 2018

Strazielle C

series ordinal

3

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11 February 2018

language of work or name

English

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publication date

1 January 2003

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11 February 2018

Behavioural Brain Research

published in

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11 February 2018

volume

138

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11 February 2018

issue

1

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11 February 2018

page(s)

71-79

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11 February 2018

Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Functional phenotype in transgenic mice expressing mutant human presenilin-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Cumulative risks of developing extrapyramidal signs, psychosis, or myoclonus in the course of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Neurobehavioral and neuropsychiatric symptoms in Alzheimer's disease: characteristics and treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Presenilins and Alzheimer's disease: biological functions and pathogenic mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Characterization of human presenilin 1 transgenic rats: increased sensitivity to apoptosis in primary neuronal cultures.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

An Alzheimer's disease-linked PS1 variant rescues the developmental abnormalities of PS1-deficient embryos.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Spontaneous alternation behavior.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Alzheimer's disease-like alterations in peripheral cells from presenilin-1 transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Behavioral Syndromes in Alzheimer’s Disease: Description and Correlates

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Rate of medial temporal lobe atrophy in typical aging and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Molecular aspects of inflammatory and immune responses in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Motor abnormalities in staggerer mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Motor coordination and spatial orientation are affected by neurofilament maldistribution: correlations with regional brain activity of cytochrome oxidase.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Spatial learning, exploration, anxiety, and motor coordination in female APP23 transgenic mice with the Swedish mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Reduced antioxidant enzyme activity in brains of mice transgenic for human presenilin-1 with single or multiple mutations.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Place navigation impaired in rats with hippocampal lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

The selective vulnerability of brainstem nuclei to Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Neuron number in the entorhinal cortex and CA1 in preclinical Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Selective preservation and degeneration within the prefrontal cortex in aging and Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

1 reference

7 January 2021

Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Single and multiple transgenic mice as models for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-4328%2802%2900230-9

7 January 2021

10.1016/S0166-4328(02)00230-9

Identifiers

DOI

1 reference

11 February 2018

PubMed ID

12493631

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11 February 2018