Neuronal nuclear organization is controlled by cyclin-dependent kinase 5 phosphorylation of Ras Guanine nucleotide releasing factor-1. (Q48442144)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Neuronal nuclear organization is controlled by cyclin-dependent kinase 5 phosphorylation of Ras Guanine nucleotide releasing factor-1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

J. Silvio Gutkind

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Sashi Kesavapany

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Ya-Li Zheng

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Niranjana Amin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Wu Ma

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Ashok B Kulkarni

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Philip Grant

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Harish C Pant

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

publication date

18 August 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

volume

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

page(s)

157-173

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

29 December 2019

cites work

1 reference

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

21 January 2018

1 reference

p35/cdk5 binds and phosphorylates beta-catenin and regulates beta-catenin/presenilin-1 interaction

21 January 2018

1 reference

Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase

21 January 2018

1 reference

Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings

21 January 2018

1 reference

Regulation of exocytosis by cyclin-dependent kinase 5 via phosphorylation of Munc18

21 January 2018

1 reference

Site-specific phosphorylation of synapsin I by mitogen-activated protein kinase and Cdk5 and its effects on physiological functions

21 January 2018

1 reference

Cdk5 is essential for synaptic vesicle endocytosis

21 January 2018

1 reference

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

21 January 2018

1 reference

Increased activity of cyclin-dependent kinase 5 leads to attenuation of cocaine-mediated dopamine signaling

21 January 2018

1 reference

Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction

21 January 2018

1 reference

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

21 January 2018

1 reference

Aberrant motor axon projection, acetylcholine receptor clustering, and neurotransmission in cyclin-dependent kinase 5 null mice

21 January 2018

1 reference

Phosphorylation of MEK1 by cdk5/p35 down-regulates the mitogen-activated protein kinase pathway

21 January 2018

1 reference

Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3.

21 January 2018

1 reference

p35/cyclin-dependent kinase 5 phosphorylation of ras guanine nucleotide releasing factor 2 (RasGRF2) mediates Rac-dependent Extracellular Signal-regulated kinase 1/2 activity, altering RasGRF2 and microtubule-associated protein 1b distribution in ne

21 January 2018

1 reference

Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29

21 January 2018

1 reference

Neurotoxicity induces cleavage of p35 to p25 by calpain

21 January 2018

1 reference

A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons

21 January 2018

1 reference

Expression of the Fe65 adapter protein in adult and developing mouse brain.

21 January 2018

1 reference

Cyclin-dependent kinase 5 (cdk5) activation requires interaction with three domains of p35.

21 January 2018

1 reference

Sites of phosphorylation by protein kinase A in CDC25Mm/GRF1, a guanine nucleotide exchange factor for Ras.

21 January 2018

1 reference

Stimulation of Ras guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) upon tyrosine phosphorylation by the Cdc42-regulated kinase ACK1

21 January 2018

1 reference

Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) following phosphorylation by the nonreceptor tyrosine kinase Src.

21 January 2018

1 reference

Phosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortex

21 January 2018

1 reference

The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium

21 January 2018

1 reference

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

21 January 2018

1 reference

The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

21 January 2018

1 reference

Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB

21 January 2018

1 reference

Basis for signaling specificity difference between Sos and Ras-GRF guanine nucleotide exchange factors

21 January 2018

1 reference

Regulation of NMDA receptors by cyclin-dependent kinase-5

21 January 2018

1 reference

Ras-GRF1 signaling is required for normal beta-cell development and glucose homeostasis

21 January 2018

1 reference

Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic beta-cells

21 January 2018

1 reference

Hippocampus-dependent learning and memory is impaired in mice lacking the Ras-guanine-nucleotide releasing factor 1 (Ras-GRF1).

21 January 2018

1 reference

A role for the Ras signalling pathway in synaptic transmission and long-term memory

21 January 2018

1 reference

Control of cyclin-dependent kinase 5 (Cdk5) activity by glutamatergic regulation of p35 stability

21 January 2018

1 reference

Integration of calcium and Ras signalling.

21 January 2018

1 reference

Control of Ras cycling by Ca2+.

21 January 2018

1 reference

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

21 January 2018

1 reference

Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

21 January 2018

1 reference

p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1159/000095130

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16921254%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference