ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein. (Q48577940)

12 February 2018

title

ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein. (English)

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12 February 2018

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6

Jared Ehrhart

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12 February 2018

Demian Obregon

1

Demian F Obregon

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12 February 2018

Jun Tan

12

Jun Tan

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12 February 2018

Takashi Mori

8

Takashi Mori

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12 February 2018

Terrence Town

11

Terrence Town

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12 February 2018

Kavon Rezai-Zadeh

2

Kavon Rezai-Zadeh

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12 February 2018

author name string

Yun Bai

3

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12 February 2018

Nan Sun

4

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12 February 2018

Huayan Hou

5

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12 February 2018

Jin Zeng

7

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12 February 2018

Gary W Arendash

9

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12 February 2018

Doug Shytle

10

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language of work or name

English

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publication date

19 April 2006

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12 February 2018

Journal of Biological Chemistry

published in

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volume

281

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12 February 2018

issue

24

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12 February 2018

page(s)

16419-16427

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12 February 2018

Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease

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21 January 2018

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Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate

21 January 2018

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Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice.

21 January 2018

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21 January 2018

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ADAM-10 protein is present in human articular cartilage primarily in the membrane-bound form and is upregulated in osteoarthritis and in response to IL-1alpha in bovine nasal cartilage

21 January 2018

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21 January 2018

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21 January 2018

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A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase

21 January 2018

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Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

21 January 2018

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21 January 2018

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The disintegrin ADAM9 indirectly contributes to the physiological processing of cellular prion by modulating ADAM10 activity

21 January 2018

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A lipid raft-associated 67kDa laminin receptor mediates suppressive effect of epigallocatechin-3-O-gallate on FcepsilonRI expression

21 January 2018

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Green tea catechin, epigallocatechin-3-gallate, inhibits vascular endothelial growth factor angiogenic signaling by disrupting the formation of a receptor complex.

21 January 2018

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Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases.

21 January 2018

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Inhibition of intestinal tumorigenesis in Apcmin/+ mice by (-)-epigallocatechin-3-gallate, the major catechin in green tea.

21 January 2018

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The green tea catechins, (-)-Epigallocatechin-3-gallate (EGCG) and (-)-Epicatechin-3-gallate (ECG), inhibit HGF/Met signaling in immortalized and tumorigenic breast epithelial cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M600617200

1 reference

12 February 2018

PubMed ID

16624814

1 reference

12 February 2018