Correction of lung inflammation in a F508del CFTR murine cystic fibrosis model by the sphingosine-1-phosphate lyase inhibitor LX2931. (Q48678102)

14 February 2018

title

Correction of lung inflammation in a F508del CFTR murine cystic fibrosis model by the sphingosine-1-phosphate lyase inhibitor LX2931. (English)

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Oleh Dzyubachyk

object named as

Oleh Dzyubachyk

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Juan B De Sanctis

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Juan B De Sanctis

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author name string

Mieke Veltman

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Marta Stolarczyk

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Gabriella Wojewodka

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Willem A Dik

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Tamas Oravecz

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Ismé de Kleer

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Bob J Scholte

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publication date

23 September 2016

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American Journal of Physiology - Lung Cellular and Molecular Physiology

published in

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volume

311

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issue

5

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page(s)

L1000-L1014

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Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion

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Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

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Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation.

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Sphingolipids in the lungs.

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The β-human chorionic gonadotropin-related peptide LQGV reduces mortality and inflammation in a murine polymicrobial sepsis model*

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Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions

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Rescue of murine F508del CFTR activity in native intestine by low temperature and proteasome inhibitors

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Ceramide in cystic fibrosis: a potential new target for therapeutic intervention

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Lipid metabolism in cystic fibrosis

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Low sphingosine-1-phosphate impairs lung dendritic cells in cystic fibrosis

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Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation

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10.1152/AJPLUNG.00298.2016

21 January 2018

Identifiers

DOI

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14 February 2018

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14 February 2018