Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways. (Q51547401)

6 April 2018

title

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways. (English)

1 reference

6 April 2018

Andrea Ballabio

7

0 references

author name string

Michela Palmieri

1

1 reference

6 April 2018

Soren Impey

2

1 reference

6 April 2018

Hyojin Kang

3

1 reference

6 April 2018

Alberto di Ronza

4

1 reference

6 April 2018

Carl Pelz

5

1 reference

6 April 2018

Marco Sardiello

6

1 reference

6 April 2018

publication date

13 July 2011

1 reference

6 April 2018

published in

Human Molecular Genetics

1 reference

6 April 2018

volume

20

1 reference

6 April 2018

issue

19

1 reference

6 April 2018

page(s)

3852-3866

1 reference

6 April 2018

Transcriptional regulatory circuits controlling mitochondrial biogenesis and function

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Energy biogenesis: one key for coordinating two genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Transcriptional coactivator PGC-1alpha promotes peroxisomal remodeling and biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Stress-sensing mechanisms in the unfolded protein response: similarities and differences between yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Signal integration in the endoplasmic reticulum unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Melanocytes and the microphthalmia transcription factor network

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Cdx2 regulates endo-lysosomal function and epithelial cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Transcriptional orchestration of the regulated secretory pathway in neurons by the bHLH protein DIMM

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Lysosomal storage disorders: emerging therapeutic options require early diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Lysosomal function in macromolecular homeostasis and bioenergetics in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Molecular mechanisms and potential therapeutical targets in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Proteomics of the lysosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

TFEB links autophagy to lysosomal biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Cell biology. Autophagy's top chef.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

An algorithm for finding signals of unknown length in DNA sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Weeder Web: discovery of transcription factor binding sites in a set of sequences from co-regulated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

NCBI GEO: mining tens of millions of expression profiles--database and tools update

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

KEGG for representation and analysis of molecular networks involving diseases and drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Supervised ensembles of prediction methods for subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

The prediction of protein subcellular localization from sequence: a shortcut to functional genome annotation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

SherLoc: high-accuracy prediction of protein subcellular localization by integrating text and protein sequence data

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

The proteome of lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Regulation of the MiTF/TFE bHLH-LZ transcription factors through restricted spatial expression and alternative splicing of functional domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

g:Profiler--a web-based toolset for functional profiling of gene lists from large-scale experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

ENCODE whole-genome data in the UCSC genome browser (2011 update)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

The vertebrate genome annotation (Vega) database

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

ASPicDB: a database resource for alternative splicing analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

HIF-1 regulation of chondrocyte apoptosis: induction of the autophagic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Chondrocyte autophagy is stimulated by HIF-1 dependent AMPK activation and mTOR suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

HIF-1α-dependent autophagy protects HeLa cells from fenretinide (4-HPR)-induced apoptosis in hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

The role of p53 in cell metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Molecular basis of variant pseudo-hurler polydystrophy (mucolipidosis IIIC)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Biogenesis of lysosome-related organelles complex 3 (BLOC-3): a complex containing the Hermansky-Pudlak syndrome (HPS) proteins HPS1 and HPS4

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Mutation of a new gene causes a unique form of Hermansky-Pudlak syndrome in a genetic isolate of central Puerto Rico

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C(alpha)-formylglycine generating enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Intracellular NOD-like receptors in host defense and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Control of macrophage activation and function by PPARs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Neuronal inactivation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) protects mice from diet-induced obesity and leads to degenerative lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Dependence of STIM1/Orai1-mediated calcium entry on plasma membrane phosphoinositides

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

SNARE-mediated membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Lysosomal exocytosis is impaired in mucolipidosis type IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Activating mutations of the TRPML1 channel revealed by proline-scanning mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Syntaxin 6, a regulator of the protein trafficking machinery and a target of the p53 family, is required for cell adhesion and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

The mannose 6-phosphate glycoprotein proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Proteomic analysis of lysosomal acid hydrolases secreted by osteoclasts: implications for lytic enzyme transport and bone metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Proteomic analysis of human lysosomes: application to monocytic and breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

A Proteomic Analysis of Lysosomal Integral Membrane Proteins Reveals the Diverse Composition of the Organelle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Integral and associated lysosomal membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Identification of novel lysosomal matrix proteins by proteome analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Identification of sites of mannose 6-phosphorylation on lysosomal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

The human brain mannose 6-phosphate glycoproteome: a complex mixture composed of multiple isoforms of many soluble lysosomal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

c-MIR, a Human E3 Ubiquitin Ligase, Is a Functional Homolog of Herpesvirus Proteins MIR1 and MIR2 and Has Similar Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

The novel genetic disorder microhydranencephaly maps to chromosome 16p13.3-12.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Fetal brain disruption sequence in sisters

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Autophagy gone awry in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Deletion of Atoh1 disrupts Sonic Hedgehog signaling in the developing cerebellum and prevents medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

FindPeaks 3.1: a tool for identifying areas of enrichment from massively parallel short-read sequencing technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

WebLogo: A Sequence Logo Generator

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

RSAT: regulatory sequence analysis tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

MicroRNA target prediction by expression analysis of host genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

HOCTAR database: a unique resource for microRNA target prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR306

21 January 2018

Identifiers

DOI

10.1093/HMG/DDR306

1 reference

6 April 2018

PubMed ID

21752829

1 reference

6 April 2018