Identification of small-molecule inhibitors of the JIP-JNK interaction. (Q51799265)

12 April 2018

title

Identification of small-molecule inhibitors of the JIP-JNK interaction. (English)

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12 April 2018

author name string

Tracy Chen

1

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12 April 2018

Natasha Kablaoui

2

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Jeremy Little

3

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Sergei Timofeevski

4

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William R Tschantz

5

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Ping Chen

6

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Junli Feng

7

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Maura Charlton

8

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Robert Stanton

9

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Paul Bauer

10

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language of work or name

English

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publication date

13 May 2009

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12 April 2018

number of pages

12

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based on heuristic

inferred from page(s)

language of work

Biochemical Journal

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volume

420

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issue

2

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page(s)

283-294

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Mammalian MAP kinase signalling cascades

cites work

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Identification of the critical features of a small peptide inhibitor of JNK activity

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Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.

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Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

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Structure-based maximal affinity model predicts small-molecule druggability.

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The critical features and the mechanism of inhibition of a kinase interaction motif-based peptide inhibitor of JNK.

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Identification of a new JNK inhibitor targeting the JNK-JIP interaction site

21 January 2018

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Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7

21 January 2018

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

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Mechanistic characterization for c-jun-N-Terminal Kinase 1alpha1.

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

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Discovery of novel isothiazole inhibitors of the TrkA kinase: structure-activity relationship, computer modeling, optimization, and identification of highly potent antagonists

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SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

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Molecular basis of MAPK-activated protein kinase 2:p38 assembly

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Kinetic mechanism and inhibitor characterization for c-jun-N-terminal kinase 3alpha1.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1042/BJ20081899

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12 April 2018

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12 April 2018