Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. (Q52603962)

4 May 2018

title

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas. (English)

1 reference

4 May 2018

Cancer Genome Atlas Research Network

1 reference

Shannon J McCall

18

0 references

25

Cancer Genome Atlas Research Network

1 reference

4 May 2018

Mirazul Islam

10

0 references

Francisco Sánchez-Vega

Francisco Sanchez-Vega

6

0 references

Alexander J. Lazar

Alexander J Lazar

23

0 references

0 references

Jose A Seoane

7

0 references

Andrew D Cherniack

5

Andrew D Cherniack

1 reference

4 May 2018

author name string

Yang Liu

1

1 reference

4 May 2018

Nilay S Sethi

2

1 reference

4 May 2018

Toshinori Hinoue

3

1 reference

4 May 2018

Barbara G Schneider

4

1 reference

4 May 2018

Farshad Farshidfar

8

1 reference

4 May 2018

Reanne Bowlby

9

1 reference

4 May 2018

Jaegil Kim

11

1 reference

4 May 2018

Walid Chatila

12

1 reference

4 May 2018

Rehan Akbani

13

1 reference

4 May 2018

Rupa S Kanchi

14

1 reference

4 May 2018

Charles S Rabkin

15

1 reference

4 May 2018

Joseph E Willis

16

1 reference

4 May 2018

Kenneth K Wang

17

1 reference

4 May 2018

Lopa Mishra

19

1 reference

4 May 2018

Akinyemi I Ojesina

20

1 reference

4 May 2018

Susan Bullman

21

1 reference

4 May 2018

Chandra Sekhar Pedamallu

22

1 reference

4 May 2018

Ryo Sakai

24

1 reference

4 May 2018

Vésteinn Thorsson

26

1 reference

4 May 2018

Adam J Bass

27

1 reference

4 May 2018

Peter W Laird

28

1 reference

4 May 2018

publication date

2 April 2018

1 reference

4 May 2018

published in

Cancer Cell

1 reference

4 May 2018

volume

33

1 reference

4 May 2018

page(s)

721-735.e8

1 reference

4 May 2018

issue

4

1 reference

4 May 2018

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

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Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance.

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Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma.

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Pembrolizumab for patients with PD-L1-positive advanced gastric cancer (KEYNOTE-012): a multicentre, open-label, phase 1b trial

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Abundant PD-L1 expression in Epstein-Barr Virus-infected gastric cancers

25 August 2018

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Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors

25 August 2018

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Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial

25 August 2018

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Common BRAF(V600E)-directed pathway mediates widespread epigenetic silencing in colorectal cancer and melanoma

25 August 2018

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ONE-CLASS DETECTION OF CELL STATES IN TUMOR SUBTYPES

25 August 2018

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Global Cancer Incidence and Mortality Rates and Trends--An Update

25 August 2018

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Common genetic variation and survival after colorectal cancer diagnosis: a genome-wide analysis

25 August 2018

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A mutational signature in gastric cancer suggests therapeutic strategies

25 August 2018

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The consensus molecular subtypes of colorectal cancer

25 August 2018

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Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes.

25 August 2018

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Hunk/Mak-v is a negative regulator of intestinal cell proliferation

25 August 2018

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Identification of indels in next-generation sequencing data

25 August 2018

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Stromal contribution to the colorectal cancer transcriptome.

25 August 2018

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25 August 2018

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Milestones of Lynch syndrome: 1895-2015.

25 August 2018

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The microsatellite instable subset of colorectal cancer is a particularly good candidate for checkpoint blockade immunotherapy

25 August 2018

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Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinoma

25 August 2018

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Global incidence of oesophageal cancer by histological subtype in 2012.

25 August 2018

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25 August 2018

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Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5966039

Comprehensive molecular characterization of gastric adenocarcinoma

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5966039

Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5966039

Inducible intestine-specific deletion of Krüppel-like factor 5 is characterized by a regenerative response in adult mouse colon

25 August 2018

1 reference

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Discovery and saturation analysis of cancer genes across 21 tumour types

25 August 2018

1 reference

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Mutational landscape and significance across 12 major cancer types

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5966039

Signatures of mutational processes in human cancer

25 August 2018

1 reference

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Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial-to-mesenchymal transition

25 August 2018

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Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer

25 August 2018

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Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity

25 August 2018

1 reference

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Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

25 August 2018

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25 August 2018

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Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

25 August 2018

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CDX2 is an amplified lineage-survival oncogene in colorectal cancer

25 August 2018

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Comprehensive molecular characterization of human colon and rectal cancer

25 August 2018

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Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis

25 August 2018

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25 August 2018

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25 August 2018

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TFAP2E-DKK4 and chemoresistance in colorectal cancer

25 August 2018

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Classification of Epstein-Barr virus-positive gastric cancers by definition of DNA methylation epigenotypes

25 August 2018

1 reference

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Intestinal development and differentiation.

25 August 2018

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25 August 2018

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RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

25 August 2018

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ContEst: estimating cross-contamination of human samples in next-generation sequencing data

25 August 2018

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Krüppel-like factor 5 is important for maintenance of crypt architecture and barrier function in mouse intestine

25 August 2018

1 reference

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Integrated genomic analyses of ovarian carcinoma

25 August 2018

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Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy

25 August 2018

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PathSeq: software to identify or discover microbes by deep sequencing of human tissue

25 August 2018

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GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

25 August 2018

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ATM activation by oxidative stress

25 August 2018

1 reference

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COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

25 August 2018

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MapSplice: accurate mapping of RNA-seq reads for splice junction discovery.

25 August 2018

1 reference

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The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis

25 August 2018

1 reference

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Signatures of mutation and selection in the cancer genome

25 August 2018

1 reference

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Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5966039

Mutations/polymorphisms in the 55 kDa subunit of DNA polymerase epsilon in human colorectal cancer

25 August 2018

1 reference

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Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling

25 August 2018

1 reference

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Transcriptional dynamics of endodermal organ formation

25 August 2018

1 reference

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Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

25 August 2018

1 reference

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Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs

25 August 2018

1 reference

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Integrated detection and population-genetic analysis of SNPs and copy number variation

25 August 2018

1 reference

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Microsatellite and chromosomal stable colorectal cancers demonstrate poor immunogenicity and early disease recurrence

25 August 2018

1 reference

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Effects of aneuploidy on cellular physiology and cell division in haploid yeast

25 August 2018

1 reference

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Prospects for the use of NK cells in immunotherapy of human cancer.

25 August 2018

1 reference

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Tetraploidy, aneuploidy and cancer

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5966039

Epigenetic stem cell signature in cancer

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5966039

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5966039

25 August 2018

1 reference

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The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer

25 August 2018

1 reference

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Circular binary segmentation for the analysis of array-based DNA copy number data

25 August 2018

1 reference

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The homeodomain protein CDX2 is an early marker of Barrett's oesophagus.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5966039

The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.

25 August 2018

1 reference

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Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

25 August 2018

1 reference

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Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5966039

Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5966039

Early-onset colorectal cancer with stable microsatellite DNA and near-diploid chromosomes

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5966039

hMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability

30 November 2018

1 reference

12 December 2020

Targeted inactivation of p53 in human cells does not result in aneuploidy

1 reference

12 December 2020

Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-β

1 reference

12 December 2020

OncoKB: A Precision Oncology Knowledge Base

1 reference

12 December 2020

10.1016/J.CCELL.2018.03.010

Identifiers

DOI

1 reference

4 May 2018

0 references

1 reference

4 May 2018