An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development. (Q54463854)

30 May 2018

title

An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development. (English)

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30 May 2018

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3

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Amiya K Patra

object named as

Amiya K Patra

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author name string

Andris Avots

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Thomas Schüler

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Albert Sickmann

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Ursula Bommhardt

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Edgar Serfling

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language of work or name

English

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publication date

23 December 2012

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30 May 2018

published in

Nature Immunology

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volume

14

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issue

2

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30 May 2018

page(s)

127-135

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30 May 2018

NFAT signaling in vertebrate development

cites work

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NFAT signaling: choreographing the social lives of cells

21 January 2018

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Transcriptional regulation by calcium, calcineurin, and NFAT

21 January 2018

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NFAT proteins: key regulators of T-cell development and function

21 January 2018

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Successive expression and activation of NFAT family members during thymocyte differentiation

21 January 2018

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The transcription factor NFAT4 is involved in the generation and survival of T cells

21 January 2018

1 reference

The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production

21 January 2018

1 reference

An enhanced immune response in mice lacking the transcription factor NFAT1.

21 January 2018

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Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development.

21 January 2018

1 reference

Cell biology of IL-7, a key lymphotrophin

21 January 2018

1 reference

Interleukin-7 can induce the activation of Jak 1, Jak 3 and STAT 5 proteins in murine T cells.

21 January 2018

1 reference

The role of Stat5a and Stat5b in signaling by IL-2 family cytokines

21 January 2018

1 reference

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

21 January 2018

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Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

21 January 2018

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Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency

21 January 2018

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Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

21 January 2018

1 reference

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

21 January 2018

1 reference

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

21 January 2018

1 reference

Stat5a/b are essential for normal lymphoid development and differentiation

21 January 2018

1 reference

Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice

21 January 2018

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Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

21 January 2018

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Bcl-2 rescues T lymphopoiesis, but not B or NK cell development, in common gamma chain-deficient mice

21 January 2018

1 reference

PKB rescues calcineurin/NFAT-induced arrest of Rag expression and pre-T cell differentiation

21 January 2018

1 reference

T cell responses in calcineurin A alpha-deficient mice

21 January 2018

1 reference

Calcineurin B1 is essential for positive but not negative selection during thymocyte development

21 January 2018

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Role of tyrosine kinases in induction of the c-jun proto-oncogene in irradiated B-lineage lymphoid cells

21 January 2018

1 reference

Role of a JAK3-dependent biochemical signaling pathway in platelet activation and aggregation

21 January 2018

1 reference

Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction

21 January 2018

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The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression

21 January 2018

1 reference

Endothelin-1-dependent nuclear factor of activated T lymphocyte signaling associates with transcriptional coactivator p300 in the activation of the B cell leukemia-2 promoter in cardiac myocytes

21 January 2018

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The specificity of JAK3 kinase inhibitors

21 January 2018

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NFATc1 affects mouse splenic B cell function by controlling the calcineurin--NFAT signaling network

21 January 2018

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GATA-3 is required for early T lineage progenitor development

21 January 2018

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An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b

21 January 2018

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A critical role for TCF-1 in T-lineage specification and differentiation

21 January 2018

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Characterization of Nfatc1 regulation identifies an enhancer required for gene expression that is specific to pro-valve endocardial cells in the developing heart.

21 January 2018

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Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

21 January 2018

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Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

21 January 2018

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IL-7 promotes the transition of CD4 effectors to persistent memory cells

21 January 2018

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Interleukin 7 regulates the survival and generation of memory CD4 cells

21 January 2018

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Alternative polyadenylation events contribute to the induction of NF-ATc in effector T cells

21 January 2018

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Characterization and analysis of the proximal Janus kinase 3 promoter

21 January 2018

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12 December 2020

Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT

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12 December 2020

Transgenic mice with hematopoietic and lymphoid specific expression of Cre

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12 December 2020

T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice

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12 December 2020

Defective lymphoid development in mice lacking Jak3

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12 December 2020

Structure-based design of specific inhibitors of Janus kinase 3 as apoptosis-inducing antileukemic agents

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12 December 2020

Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3

1 reference

12 December 2020

A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8- triple-negative adult mouse thymocytes defined by CD44 and CD25 expression.

1 reference

12 December 2020

The trophic action of IL-7 on pro-T cells: inhibition of apoptosis of pro-T1, -T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways.

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12 December 2020

Identifiers

DOI

10.1038/NI.2507

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30 May 2018

release_or6yvt72lvhzfny7hshh2gbxvy

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/or6yvt72lvhzfny7hshh2gbxvy

24 November 2022

mapped directly with Wikidata item

PubMed ID

23263556

1 reference

30 May 2018