Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells. (Q54579340)

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5 February 2020

title

Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells (English)

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5 February 2020

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B-cell chronic lymphocytic leukemia

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8

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5 February 2020

Mario A Pagano

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5 February 2020

Anna Maria Brunati

2

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5 February 2020

Francesca Zonta

3

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Federica Frezzato

4

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5 February 2020

Enrico Gringeri

7

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Livio Trentin

10

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5 February 2020

author name string

E Tibaldi

1

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5 February 2020

C Gattazzo

5

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R Zambello

6

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publication date

24 June 2011

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5 February 2020

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5 February 2020

volume

25

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issue

11

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page(s)

1768-1781

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https://scigraph.springernature.com/pub.10.1038/leu.2011.152

5 February 2020

exact match

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cites work

Chronic lymphocytic leukemia: revelations from the B-cell receptor.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Differential signaling via surface IgM is associated with VH gene mutational status and CD38 expression in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Interference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Regulation of B cell fates by BCR signaling components

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Regulation of B-cell fate by antigen-receptor signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Cutting edge: essential role of phospholipase C-gamma 2 in B cell development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

B cell antigen receptor signaling: roles in cell development and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Positive and negative roles of the tyrosine kinase Lyn in B cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in B-CLL: association with protein kinase Cdelta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

PI3-kinase regulates survival of chronic lymphocytic leukemia B-cells by preventing caspase 8 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

ITAM-mediated tonic signalling through pre-BCR and BCR complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

The specificities of protein kinase inhibitors: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

The function of the protein tyrosine phosphatase SHP-1 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

PTP1B and TC-PTP: novel roles in immune-cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

The unique antigen receptor signaling phenotype of B-1 cells is influenced by locale but induced by antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Natural phosphorylation of CD5 in chronic lymphocytic leukemia B cells and analysis of CD5-regulated genes in a B cell line suggest a role for CD5 in malignant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

A SHPing tale: perspectives on the regulation of SHP-1 and SHP-2 tyrosine phosphatases by the C-terminal tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

alpha-bromoacetophenone derivatives as neutral protein tyrosine phosphatase inhibitors: structure-Activity relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCdelta and proteasome-dependent regulation of Mcl-1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Tyrosine phosphorylation mediates both activation and downmodulation of the biological activity of Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Mcl-1; the molecular regulation of protein function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Mcl-1 is a potential therapeutic target in multiple types of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Vav-family proteins in T-cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Inhibitory receptors signal activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

Regulating Vav1 phosphorylation by the SHP-1 tyrosine phosphatase is a fine-tuning mechanism for the negative regulation of DISC formation and Fas-mediated cell death signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

High Mda-7 expression promotes malignant cell survival and p38 MAP kinase activation in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

B7 costimulatory molecules from malignant cells in patients with b-cell chronic lymphoproliferative disorders trigger t-cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

inferred from DOI database lookup

7 January 2021

based on heuristic

Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152

inferred from DOI database lookup

7 January 2021

based on heuristic

Negative regulation of antigen receptor-mediated signaling by constitutive association of CD5 with the SHP-1 protein tyrosine phosphatase in B-1 B cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.152